"Internet and world-wide-web platforms, big data analytics, software, social media and civic technologies allow for the creation of smart ecosystems in which connected intelligence emerges and disruptive social and eco-innovation flourishes. This book focuses on three grand challenges that matter for any territory, no matter where it is located: (i) smart growth, a path that more and more cities, regions and countries are adopting having realised the unlimited potential of growth that is based on knowledge, innovation and digital technologies; (ii) safety and security, which is a pre-requisite for quality of life in a world of intense social, natural and technological threats; and (iii) sustainability, use of renewable energy, protection of living ecosystems, addressing climate change and global warming in a period of rapid urbanisation that makes established sustainability models and planning patterns quickly obsolete. The core argument of the book is that problem-solving and novel solutions to these grand challenges emerge in smart ecosystems that physically and digitally connect unrelated areas of knowledge, methods from different disciplines of science and technology and infrastructures and resources distributed over a large number of individuals, organisations, and places. This book will be of interest to students and researchers of urban and regional studies, innovation studies, economic geography and urban planning, as well as urban policymakers".