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Library | Item Barcode | Call Number | Material Type | Item Category 1 | Status |
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Searching... | 30000010167538 | QD421.A1 A44 2006 | Open Access Book | Book | Searching... |
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Summary
Summary
This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than forty years, The Alkaloids: Chemistry and Biology, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of this rapidly expanding field. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids.
Author Notes
Professor Emeritus Geoffrey A. Cordell obtained his Ph.D. in synthetic natural product chemistry at the University of Manchester in 1970. After two years as a NATO postdoctoral fellow at the Department of Chemistry, M.I.T., he joined the College of Pharmacy, University of Illinois at Chicago (UIC). A Professor since 1980, he served as a Department Head for 12 years and as Interim Dean of the College of Pharmacy for almost three years, as well as holding several other senior academic and research administrative positions at the Department, College, and Campus levels. He was the Co-founder of the US - Thai Consortium for Pharmacy Education, which developed and trained faculty for six new schools of pharmacy in Thailand. He retired from the University of Illinois in 2007. Since 1983, he has served as President of Natural Products Inc., a consulting company.
He is the author of about 600 research publications, book chapters, comprehensive reviews and professional publications; is the author of two books, with three more in progress; the editor of 37 books, including 29 volumes in the series "The Alkaloids: Chemistry and Biology"; is Associate Editor-in-Chief of the Chinese Journal of Natural Medicines; and a member of the Editorial Advisory Board of 26 international scientific journals. He is a former President of the American Society of Pharmacognosy, and is also an Honorary Member.
In 1981, he was an Alexander von Humboldt Fellow at the University of Munich with Professor Hildebert Wagner. He is an elected Fellow of the Royal Chemical Society, the Linnean Society of London, the American Society of Pharmacognosy, and the American Association of Pharmaceutical Scientists. In addition to assisting international organizations and corporations in several countries around the world to develop their research and academic programs, he is an Honorary Professor at Sichuan University, Chengdu, China; and at Amity University, Noida, India. He is also a Visiting Professor at universities in Peru, Malaysia, and Brasil, and an International Collaborative Partner of the UTAR Global Research Network in Malaysia in the areas of biodiversity and cancer. In addition, he is a member of the International Advisory Board of several natural product research institutes. His interests include the chemistry and biosynthesis of alkaloids, the sustainability and quality control of medicinal agents, the remote detection of biologically active natural products, and the use of vegetables as chemical reagents.
Table of Contents
Contributors | p. vii |
Preface | p. ix |
Regulation of Alkaloid Biosynthesis in PlantsPeter J. Facchini | |
I Introduction | p. 1 |
II Alkaloid Biosynthetic Pathways | p. 2 |
III Regulation of Alkaloid Biosynthesis | p. 16 |
IV Applications of Genomics to the Study of Alkaloid Biosynthesis | p. 28 |
V Metabolic Engineering of Alkaloid Pathways | p. 29 |
VI Future Prospects | p. 34 |
Acknowledgments | p. 35 |
References | p. 35 |
Ergot Alkaloids - Biology and Molecular BiologyChristopher L. Schardl and Daniel G. Panaccione and Paul Tudzynski | |
I Introduction | p. 45 |
II Through the Ages: A History of Ergot Alkaloid Use, Abuse, and Poisoning | p. 48 |
III Ergot Alkaloid Producers | p. 50 |
IV Biosynthetic Pathways and Genes | p. 53 |
V Routine Analytical Methods for Ergot Alkaloids | p. 75 |
VI Ergot Alkaloid Activities and Roles | p. 76 |
VII Summary and Conclusions | p. 80 |
Acknowledgments | p. 82 |
References | p. 82 |
Chemical and Biological Aspects of Narcissus AlkaloidsJaume Bastida and Rodolfo Lavilla and Francesc Viladomat | |
I Introduction | p. 87 |
II Narcissus Alkaloids and their Occurrence | p. 91 |
III Biosynthetic Pathways | p. 99 |
IV Synthetic Studies | p. 114 |
V Spectroscopy and Alkaloid Data | p. 127 |
VI Biological and Pharmacological Activities | p. 153 |
References | p. 163 |
Bisindole AlkaloidsToh-Seok Kam and Yeun-Mun Choo | |
I Introduction | p. 182 |
II Indole-Indole and Tryptamine-Tryptamine Type, and Related Alkaloids | p. 182 |
III Tryptamine-Tryptamine Type with an Additional Monoterpene Unit and Related Alkaloids | p. 216 |
IV Corynanthe-Tryptamine Type | p. 217 |
V Corynanthe-Corynanthe Type | p. 223 |
VI Corynanthe-Strychnos Type | p. 224 |
VII Vobasine-Tryptamine Type | p. 228 |
VIII Vobasine-Vobasine Type | p. 228 |
IX Vobasine-Akuammiline Type | p. 230 |
X Vobasine-Vincorine Type | p. 231 |
XI Bisindole Alkaloids from Alstonia | p. 231 |
XII Akuammiline-Ajmaline Type | p. 240 |
XIII Ajmaline-Vincorine Type | p. 242 |
XIV Akuammiline-Vincorine Type | p. 243 |
XV Akuammiline-Pleiocarpamine Type | p. 245 |
XVI Vincorine-Vincorine Type | p. 245 |
XVII Strychnos-Vobasine Type | p. 247 |
XVIII Strychnos-Strychnos Type | p. 248 |
XIX Secodine-Secodine Type | p. 255 |
XX Apparicine-Vobasine Type | p. 255 |
XXI Ellipticine-Ellipticine Type | p. 257 |
XXII Iboga-Vobasine Type | p. 258 |
XXIII Iboga-Iboga Type | p. 269 |
XXIV Aspidosperma-Vobasine Type | p. 270 |
XXV Aspidosperma-Vincorine Type | p. 270 |
XXVI Aspidosperma-Macroline Type | p. 271 |
XXVII Aspidosperma-Iboga Type | p. 273 |
XXVIII Aspidosperma-Aspidosperma Type | p. 274 |
XXIX Aspidosperma-Pseudoaspidosperma Type | p. 286 |
XXX Aspidosperma-Eburnea Type | p. 289 |
XXXI Aspidosperma-Canthinone Type | p. 294 |
XXXII Eburnea-Eburnea Type | p. 297 |
XXXIII Miscellaneous Bisindole Alkaloids | p. 298 |
XXXIV Aspidosperma-Cleavamine Type | p. 300 |
References | p. 322 |
Cumulative Index of Titles | p. 339 |
Index | p. 347 |