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Cover image for Polymeric drugs and drug administration
Title:
Polymeric drugs and drug administration
Publication Information:
Washington, D.C. : American Chemical Society, 1994
ISBN:
9780841227446
General Note:
Developed from a Symposium sponsored by the Division of Polymer Chemistry, Inc, at the American Chemical Society, Washington, DC, August 23-28, 1992
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30000003157272 RS201.P65 P64 1994 Open Access Book Proceedings, Conference, Workshop etc.
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Summary

Summary

Presents recent advances in polymeric materials designed as drugs and for drug administration. Discusses polymer characteristics, micelle formation, hydrogels, and drug release based on the electrical impulses on polymers. Examines polymer-based systems for treatment of inflammation, oncology and diabetes, prevention of gastric ulcers, and management of central nervous system conditions. Describes computer simulations of interactions between solvents and polymer matrices.


Table of Contents

Polymer Systems for Biomedical Applications: An OverviewR.M. Ottenbrite and N. Fadeeva
Bioelastic Materials and the DTt-Mechanism in Drug DeliveryD.W. Urry and D.C. Gowda and C.M. Harris and R.D. Harris
Sequence-Selective Binding of DNA by Oligopeptides as a Novel Approach to Drug DesignM. Lee and C. Walker
Protein Device for Glucose-Sensitive Release of InsulinY. Ito and Y. Imanishi
Preparation and Characterization of Enzyme-Digestible Hydrogels from Natural Polymers by Gamma IrradiationK.R. Kamath and K. Park
Pharmacokinetics and Toxicity of a p-Boronophenylalanine-Cyclodextrin Formulation Delivered by Intravenous Infusion to DogsT.R. LaHann and W.F. Bauer and P. Gavin and D.R. Lu
Electrorelease of Drugs from Composite Polymer FilmsM.Hepel and Z. Fijalek
Pulsatile Drug Release by Electric StimulusY.H. Bae and I.C. Kwon and S.W. Kim
Poly(ethylene oxide)-Based Delivery Systems: Influence of Polymer Molecular Weight and Gel Viscoelastic Behavior on Drug Release MechanismA. Apicella and B. Cappello and M.A. Del Nobile and M.I. La Rotonda and G. Mensitieri and L. Nicolais and S. Seccia
Development of Micelle-Forming Polymeric Drugs with Superior Anticancer ActivityM. Yokoyama and G. S. Kwon and T. Okano and Y. Sakurai and K. Kataoka
Optimization of Poly(maleic acid-alt-2-cyclohexyl-1,3-dioxepin-5-ene) for Anti-Human Immunodeficiency Virus ActivityJ.L. Ding and R.M. Ottenbrite
Enhancement of Cell Membrane Affinity and Biological Activity of Polyanionic PolymersY. Suda and S. Kusumoto and N. Oky and R.M. Ottenbrite
Accumulation of Poly(vinyl alcohol) at Inflammatory SiteT. Yamaoka and Y. Tabata and Y. Ikada
Design of New Building Blocks in Resorbable Polymers: Application in Drug Delivery MicrospheresA.-C. Albertsson and A. Lofgren and C. Sturesson and M. Sjoling
Chain Structure and Hydrolysis of Nonalternating Polyester AmidesK.E. Gonsalves and X. Chen
Polymeric Site-Directed Delivery of Misoprostol to the StomachP.W. Collins and S.J. Tremont and W.E. Perkins and R.L. Fenton and M.P. McGrath and G. M. Wagner and A. F. Gasiecki and R.G. Bianchi and J.J. Casler and C.M. Ponte and J.C. Stolzenbach and P.H. Jones and D. Forster
Use of a-1,4-Polygalactosamine as a Carrier of Macromolecular Prodrug of 5-FluorouracilT. Ouchi and K. Inosaka and Y. Ohya
Poly(methacrylic acid) Hydrogels for Rumen Bypass and the Delivery of Oral Vaccines to RuminantsT.P. Bowersock and W.S.W. Shalaby and W.E. Blevins and M. Levy and K. Park
Polymer-Solvent Interactions Studied with Computational ChemistryS.J. Lee and K. Park
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