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Cover image for Stem cell engineering : principles and applications
Title:
Stem cell engineering : principles and applications
Publication Information:
Heidelberg ; New York : Springer, c2011
Physical Description:
xli, 547 p. : ill. (some col.), ports. ; 24 cm.
ISBN:
9783642118647

9783642118654

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Material Type
Item Category 1
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30000010275377 QH588.S83 S748 2011 Open Access Book Book
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Summary

Summary

The potential of stem cells for healing and disease prevention in all fields of medicine is tremendous and has revolutionized the high-tech biomedical research. In this book, many of the most prominent researchers discuss the challenging topics of stem cell engineering, for example:Ethical issues of stem cell research; technological challenges, stem cell growth and differentiation, therapeutic applications, bioreactors and bioprocesses, high throughput and microfluidic screening platforms, stem cell identification and sorting, intercellular signaling and engineered niches, novel approaches for embryonic and adult stem cell growth and differentiation, stem cells and drug discovery, screening platforms.Stem Cell Engineering offers valuable background and reference for both the public and professionals including industrial staffers, faculty, researchers, engineers, students and scientific journalists.


Table of Contents

Ilya Digel and Aysegül Temiz ArtmannPaolo Di Nardo and Marilena Minieri and Arti AhluwaliaEdda TobiaschIsgard S. Hueck and Martin Haas and Rita Finones and Jane Frimodig and David A. GoughPaul R. Bidez III and J. Yasha Kresh and Yen Wei and Peter I. LelkesSabrina Gordon-Keylock and Lesley ForresterNicole M. Kane and Chris Denning and Andrew H. BakerOlivier Preynat-Seauve and Karl-Heinz Krause and Jean VillardFrank R. Kloss and Sarvpreet Singh and Günter LepperdingerStefanie Keymel and Burcin Özüyaman and Marijke Grau and Malte Kelm and Petra KleinbongardMatthew J. Dalby and Richard O.C. OreffoJohn Paul Kirton and Tsung-Neng Tsai and Qingbo XuMelissa A. Brown and Cindy S. Cheng and George A. TruskeyW.W. Minuth and L. Denk and A. RoessgerChristoph Becker and Katrin Montzka and Gerhard JakseRylie A. Green and Penny J. Martens and Robert Nordon and Laura A. Poole-WarrenMichael Gelinsky and Anja Lode and Anne Bernhardt and Angela Rösen-WolffThomas Brevig and Robin Wesselschmidt and Masayuki YamatoHwal (Matthew) SuhJan Pruszak and Máté Döbrössy and Jochen Kieninger and Kuppusamy Aravindalochanan and Gerald A. Urban and Guido NikkhahStefan Golz and Andreas Geerts and Andreas WilmenBernd Denecke and Silke SchwengbergOmonigho A. Aisagbonhi and Antonis K. Hatzopoulos
Part I Instead of an Introduction - The Emperor's New Legs
The Emperor's New Body: Seeking for a Blueprint of Limb Regeneration in Humansp. 3
Part II Basics and Basic Research
Engineering the Stem Cell Niche and the Differentiative Micro- and Macroenvironment: Technologies and Tools for Applying Biochemical, Physical and Structural Stimuli and Their Effects on Stem Cellsp. 41
Differentiation Potential of Adult Human Mesenchymal Stem Cellsp. 61
The Potential of Selectively Cultured Adult Stem Cells Re-implanted in Tissuesp. 79
Enhanced Cardiac Differentiation of Mouse Embryonic Stem Cells by Electrical Stimulationp. 119
The Therapeutic Potential of ES-Derived Haematopoietic Cellsp. 143
Genetic Modification of Human Embryonic and Induced Pluripotent Stem Cells: Viral and Non-viral Approachesp. 159
The Immune Barriers of Cell Therapy with Allogenic Stem Cells of Embryonic Originp. 181
Reponses of Mesenchymal Stem Cells to Varying Oxygen Availability In Vitro and In Vivop. 199
Endothelial Progenitor Cells and Nitric Oxide: Matching Partners in Biomedicinep. 213
Skeletal Stem Cells and Controlled Nanotopographyp. 247
Part III Clinical Applications
Cells and Vascular Tissue Engineeringp. 261
Endothelial Progenitor Cells for Vascular Repairp. 297
Regenerating Tubules for Kidney Repairp. 321
Stem Cells in Tissue Engineering and Cell Therapies of Urological Defectsp. 345
Bio-synthetic Encapsulation Systems for Organ Engineering: Focus on Diabetesp. 363
Stem Cell Engineering for Regeneration of Bone Tissuep. 383
Part IV Techniques and Applications
Building, Preserving, and Applying Extracellular Culture Integrity Using New Cell Culture Methods and Surfacesp. 403
Fabrication of Modified Extracellular Matrix for the Bone Marrow-Derived Mesenchymal Stem Cell Therapeuticsp. 417
Neural Stem Cells: From Cell Fate and Metabolic Monitoring Toward Clinical Applicationsp. 435
Adult Stem Cells in Drug Discoveryp. 457
Embryonic Stem Cells as a Tool for Drug Screening and Toxicity Testingp. 473
Embryonic Stem Cells: A Biological Tool to Translate the Mechanisms of Heart Developmentp. 501
Indexp. 521
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