Cover image for Negative strand RNA virus
Title:
Negative strand RNA virus
Publication Information:
Singapore ; Hackensack, NJ : World Scientific, c2011
Physical Description:
viii, 314 p. : ill. ; 24 cm.
ISBN:
9789814317221
Subject Term:
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30000010294306 QR395 N44 2011 Open Access Book Book
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Summary

Summary

Negative strand RNA viruses have a unique mechanism of replication. Their genome is a single strand RNA that has to be transcribed as soon as the virus enters the host in order to carry out viral replication. As a result, a viral-specific RNA polymerase is packaged in the virion and is ready for transcription after virus entry. This novel replication mechanism dictates the assembly and RNA synthesis of negative strand RNA viruses. In recent years, many discoveries have been made with regard to the entry, replication and assembly of this class of viruses. This book will present updated coverage of the fundamental knowledge about negative strand RNA viruses.


Table of Contents

Biao HeAurélie Albertini and Yves GaudinMasato TsurudomeGail Williams Wertz and Summer E. Galloway and Djamila HarouakaTomoaki Ogino and Amiya K. BanerjeeSonia LonghiAmal A. Rahmeh and Sean P. J. WhelanDebasis Panda and Asit K. PattnaikMing Luo and Todd J. Green and Z. Hong ZhouMegan S. Harrison and Takemasa Sakaguchi and Anthony P. SchmittDouglas S. LylesDenis GerlierJohn N. BarrPeter Halfmann and Gabriele Neumann and Yoshihiro Kawaoka
Forewordp. vii
Chapter 1 Overview of Negative-Strand RNA Virusesp. 1
Chapter 2 Rhabdovirus Entry into the Host Cellp. 15
Chapter 3 Virus Entry: Parainfluenza Virusesp. 35
Chapter 4 What Controls the Distinct VSV RNA Synthetic Processes of Replication and Transcription?p. 63
Chapter 5 mRNA Capping by Vesicular Stomatitis Virus and Other Related Virusesp. 79
Chapter 6 Structural Disorder within the Measles Virus Nucleoprotein and Phosphoprotein: Functional Implications for Transcription and Replicationp. 95
Chapter 7 Biochemical and Structural Insights into Vesicular Stomatitis Virus Transcriptionp. 127
Chapter 8 Transcription of Vesicular Stomatitis Virus RNA Genomep. 149
Chapter 9 Assembly of Vesicular Stomatitis Virusp. 175
Chapter 10 Paramyxovirus Budding Mechanismsp. 193
Chapter 11 Virus-Host Interaction by Members of the Family Rhabdoviridae and Filoviridaep. 219
Chapter 12 Paramyxovirus and Rig-Like Helicases: A Complex Molecular Interplay Driving Innate Immunityp. 243
Chapter 13 The Molecular and Cellular Biology of Emerging Bunyavirusesp. 261
Chapter 14 Ebolaviruses: What We Know and Where We Are on Potential Therapeuticsp. 295
Indexp. 309