Summary

The biomolecular basis underlying essential hypertension and end organ damage associated with hypertension is characterized as polygenic diseases with complexities such as "environment gene" and "gene-gene" interactions. Despite intensive research in this field, this molecular book is aimed at providing the state-of-the-art reviews which define how the biologic systems sense changes in environment, alter their activities or function, and cross talk with other neurohormonal systems to modulate cardiovascular/renal function and blood pressure. This title will attract scientists and investigators in both academic and industrial fields, and clinicians.