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Library | Item Barcode | Call Number | Material Type | Item Category 1 | Status |
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Searching... | 30000010164176 | QP531 C74 2008 | Open Access Book | Book | Searching... |
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Summary
Summary
The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. The present text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten and chromium. The final three chapters provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment.
Author Notes
Robert Crichton is Emeritus Professor, Faculty of Science, Universite Catholique de Louvain in Belgium. He has some forty years experience in teaching the subject, and published over 200 scientific articles and a number of books. Since 1985 he has organized a series of over twenty advanced courses on Metals in Biology in Louvain-la-Neuve, which have trained over 1300 doctoral and post-doctoral students, many of whom are today leaders in the field.
The Second Edition of Biological Inorganic Chemistry: An Introduction to Molecular Structure and Function received the 2013 TEXTY Textbook Excellence Award in Physical Sciences from the Text and Academic Authors Association.
Table of Contents
The role of metals in biology an overview |
Basic coordination chemistry for biologists |
Structural and molecular biology for chemists |
Biological ligands for metal ions |
An overview of intermediary metabolism and bioenergetics |
Methods which can be used to study metals in biology |
Metal assimilation pathways |
Transport, storage and homeostasis of metal ions |
Sodium and potassium |
Calcium |
Magnesium |
Zinc |
Iron |
Copper |
Nickel and cobalt |
Manganese |
Molybdenum, vanadium, tungsten and chromium |
Metals in brain function |
Biomineralisation |
Metals in medicine and the environment |
Concluding remarks |