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Cover image for Molecular evolution : computer analysis of protein and nucleic acid sequences
Title:
Molecular evolution : computer analysis of protein and nucleic acid sequences
Series:
Methods in enzymology; v183
Publication Information:
San Diego, CA : Academic Press, 1990
ISBN:
9780121820848
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30000002481665 QP625.N89 M64 1990 Open Access Book Book
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Summary

Summary

This volume addresses a variety of areas in which computers are used to manage and manipulate nucleic acid and protein sequence data. The manipulations include searching, aligning, and determining the significance of similarities, as well as the construction of phylogenetic trees that show the evolutionary history of related sequences. Ready-to-use methods for the "at-the-bench" scientist are presented.


Table of Contents

DatabasesC. Burks et al.
GenBank: Current Status and Future DirectionsP. Kahn and G. Cameron
EMBL Data Library
W.C. BarkerD.G. George and L.T. Hunt
Protein Sequence DatabaseB. Keil
Cooperation between Databases and Scientific Community
Searching DatabasesW.R. Pearson
Rapid and Sensitive Sequence Comparison with FASTP and FASTAR.F. Doolittle
Searching through Sequence DatabasesS. Henikoff and J.C. Wallace and J.P. Brown
Finding Protein Similarities with Nucleotide Sequence DatabasesC.B. Lawrence
Use of Homology Domains in Sequence Similarity DetectionM. Gribskov and R. L
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