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Library | Item Barcode | Call Number | Material Type | Item Category 1 | Status |
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Searching... | 30000010169018 | QH442 R44 2007 | Open Access Book | Book | Searching... |
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Summary
Summary
This text presents an introduction to the concepts and techniques of recombinant DNA research and their dramatic results. It explores core concepts in molecular biology in a contemporary inquiry-based context, building its coverage around the landmark experiments that redefined our understanding of DNA.
Author Notes
James Dewey Watson James D. Watson was born on April 6, 1928. Watson was an extremely industrious student and entered the University of Chicago when he was only 15. He received his Bachelor of Science degree in Zoology four years later, and went on to earn a Ph.D. in the same subject at Indiana University. He was performing research at the University of Copenhagen in Denmark, when he first learned of the biomolecular research at the Cavendish Laboratory of Cambridge University in England. Watson joined Francis Crick in this work in 1951.
At the age of 25, he and colleague Crick discovered the structure of DNA, the double helix. Watson went on to become a Senior Research Fellow in Biology at the California Institute of Technology, before returning to Cambridge in 1955. The following year he moved to Harvard University, where he became Professor of Biology, a post he held until 1976. Watson and Crick won the 1962 Nobel Laureate in Medicine for their discoveries concerning the molecular structure of nuclear acids and its significance for information transfer in living material. In 1968, Watson published his account of the DNA discovery, "The Double Helix." The book became an international best-seller.
Watson became the Director and later President of the Cold Spring Harbor Laboratory. In 1988 he served as Director of the Human Genome Project at the National Institutes of Health, a massive project to decipher the entire genetic code of the human species. Watson has received many awards and medals for his work, along with the Nobel Prize, he has also received the Presidential Medal of Freedom.
(Bowker Author Biography)
Table of Contents
Foundations of DNA |
Overview |
DNA is the Primary Genetic Material |
From DNA to Protein |
Basics of Gene Expression |
Basic Tools of Recombinant DNA |
Fundamental Features of Genes |
Getting DNA into Cells and Organisms |
Moveable Elements |
Epigenetics |
RNAi |
Foundations of Genomics |
Overview |
Sequencing a Small Genome |
How the Human Genome was Sequenced |
Analyzing Genomes |
Overview |
Sequence Analysis |
Genome-wide Functional Analysis |
Genomic Approaches to Human Biology |
Hunting Human Disease Genes |
Cancer Genomics |
DNA and Justice |