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Library | Item Barcode | Call Number | Material Type | Item Category 1 | Status |
|---|---|---|---|---|---|
Searching... | 30000000281463 | QH324.9.N8 P56 1984 | Open Access Book | Book | Searching... |
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Summary
Summary
Phosphorous-31 NMR: Principles and Applications focuses on the evolution of phosphorus-31 nuclear magnetic resonance (NMR) as a widely applied spectroscopic probe of the structure and dynamics of phosphorus-containing compounds. The selection first offers information on the principles and empirical observations of phosphorus-31 chemical shifts and the principles and applications of phosphorus-31 spin-spin coupling constants. Discussions focus on introduction and basic principles, directly bonded phosphorus coupling constants, and two-bond and three-bond coupling constants. The text then ponders on phosphorus-31 NMR of enzyme complexes and paramagnetic probes of enzyme complexes with phosphorus-containing compounds. The manuscript elaborates on the use of chiral thiophosphates and the stereochemistry of enzymatic phosphoryl transfer and DNA and RNA conformations. Topics include helix-coil transitions, sequence dependence of double-stranded DNA conformations, dynamic behavior of RNA and DNA, biological and genetic significance, and stereochemical problems studied with chiral thiophosphates. The conformation and dynamics of nucleic acids and phosphoproteins, relaxation behavior of nucleic acids, and theory and applications of solid-state phosphorus-31 NMR to nucleic acids are also discussed. The selection is a valuable reference for readers interested in the principles and applications of phosphorus-31 nuclear magnetic resonance.
Table of Contents
| Contributors |
| Preface |
| IntroductionD.G. Gorstein |
| Phosphorus-31 Chemical Shifts and Spin-Spin Coupling Constants: Principles and Empirical Observations |
| Phosphorus-31 Chemical Shifts: Principles and Empirical ObservationsD.G. Gorenstein |
| Phosphorous-31 Spin-Spin Coupling Constants: Principles and ApplicationsD.G. Gorenstein |
| Theory and Applications of Phosphorus-31 NMR to Biochemistry |
| Phosphorus-31 NMR of Enzyme ComplexesB.D. Nageswara Rao |
| 31 P-NMR Studies of PhosphoproteinsH.J. Vogel |
| Paramagnetic Probes of Enzyme Complexes with Phosphorus-Containing CompoundsJ.J. Villafranca |
| Use of Chiral Thiophosphates and the Stereochemistry of Enzymatic Phosphoryl TransferM.-D. Tsai |
| Use of Chiral [ 16 O, 17 O, 18 O] Phosphate Esters to Determine the Stereochemical Course of Enzymatic Phosphoryl Transfer ReactionsJ.A. Gerlt |
| DNA and RNA ConformationsC.-W. Chen and J.S. Cohen |
| High-Resolution 31 P-NMR Spectroscopy of Transfer Ribonuclei AcidsD.G. Gorenstein |
| Phosphorus-31 NMR of Drug-Nucleic Acid ComplexesD.G. Gorenstein and E.M. Goldfield |
| Phosphorus Relaxation Methods: Conformation and Dynamics of Nucleic Acids and PhosphoproteinsP.A. Hart |
| Relaxation Behavior of Nucleic Acids: Dynamics and StructureT.L. James |
| Solid-State Phosphorus-31 NMR: Theory and Application to Nucleic AcidsH. Shindo |
| Phosphorus-31 NMR of Phospholipids in MicellesE.A. Dennis and A. Pluckthuuml;n |
| Phosphorus-31 NMR of Phospholipids in MembranesI.C.P. Smith and I.H. Ekiel |
| Application to Biology and Medicine: Future Directions |
| Two-Dimensional Phosphorus-31 NMRW.C. Hutton |
| Identification of Diseased States by Phosphorus-31 NMRM. Baacute;raacute;ny and T. Glonek |
| Selected Data |
| Appendixes: Selected Compilation of 31 P-NMR DataD.G. Gorenstein and D.O. Shah |
| Appendix I Doubly Connected Phosphorus |
| Appendix II Triply Connected Phosphorus |
| Appendix III Quadruply Connected Phosphorus |
| Appendix IV Quintuply Connected Phosphorus |
| Appendix V Sextuply Connected Phosphorus |
| Index |
