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Cover image for Tissue engineering, stem cells, and gene therapies
Title:
Tissue engineering, stem cells, and gene therapies
Series:
Advances in experimental medicine and biology
Publication Information:
New York : Kluwer Academic/Plenum Publishers, 2003
ISBN:
9780306477881
General Note:
534

Proceedings of BIOMED 2002, the 9th International Symposium on Biomedical Science and Technology, held September 19-22, 2002, in Antalya, Turkey
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30000010018897 R856.A2 I58 2003 Open Access Book Proceedings, Conference, Workshop etc.
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Summary

Summary

Recent years have seen an upsurge of significant interest in cell-based technologies. A range of productive and lively debate have taken place relating to tissue engineering, namely the construction of tissues and whole organs using molecularly-designed resorbable biomaterials to create tissue de novo, the potential use of human embryonic stem cells for transplantation and regenerative medicine, with similar potential for adult-derived stem cells, and gene therapy, in relation to cell transplantation. New findings in biomimetic materials, cell signalling pathways, extracellular matrix receptors and ligands, growth factors, and the human genome project, all present particularly motivating sources for the development of research in the evergrowing biomedical field. The purpose of this book is to stimulate further the work in biomedicine and to make the issues of related scientific disciplines accessible to a wider readership by characterising the current state of research in the biomedical field. The lectures and a selection of the presentations from BlOMED 200- th The 9 International Symposium on Biomedical Science and Technology, held in September 2002 in Turkey- constitute the basis for the volume. Tissue engineering, stem cells, cell and gene therapies were the major topics presented and discussed in the symposium. This book is intended to serve as an up-to-date synopsis of the major developments of our area through the work reflected in BlOMED 2002, though not covering all aspects of the topics, due to the natural restrictions within a volume of this kind.


Table of Contents

R. NeremJ. McWhir and A. Thomson and V. SottileP. HenonE. KansuV. Dixit and Y. M. ElcinR. G. BretzelYe. V. Pankratov and A. I. Ivanov and T. D. Kolokoltsova and Ye. A. Nechayeva and I. F. Radayeva and L. I. Korochkin and A. V. Revischin and S. A. Naumov and I. A. Khlusovi and A. I. AutenshlusT. DemirerY.-S. Weng and H.-Y. Lin and Y.-J. Hsiang and C.-T. Hsieh and W.-T. LiH. Rodriguez and P. Jaruga and M. Birincioglu and P. E. Barker and C. O'Connell and M. DizdarogluC. O'Connell and P. E. Barker and M. Marino and P. McAndrew and D. H. Atha and P. Jaruga and M. Birincioglu and M. Dizdaroglu and H. RodriguezS. Zhang and C. E. SeminoM. Crombez and D. MantovaniL. Bacakova and M. Lapcikova and D. Kubies and F. RypacekV. Proks and L. Machova and S. Popelka and F. RypacekP. B. Malafaya and M. E. Gomes and A. J. Salgado and R. L. ReisG. Khang and S. J. Lee and C. W. Han and J. M. Rhee and H. B. LeeM. Bokhari and M. Birch and G. AkayY. M. Elcin and A. E. Elcin and R. G. Bretzel and T. LinnM. M. Marques and A. J. Thomson and J. McWhirD. S. Keskin and V. HasirciA. Arman and P. E. AuronA. Muvaffak and N. HasirciB. Erdag and B. K. Balcioglu and A. Kumbasar and B. Cirakoglu
I. Perspectives for Tissue Engineering and Stem Cells
1. Tissue engineering: confronting the transplantation crisisp. 1
2. Human embryonic stem cells- realising the potentialp. 11
3. Human embryonic or adult stem cells: an overview on ethics and perspectives for tissue engineeringp. 27
4. Stem cell biology and plasticityp. 47
II. Stem Cells in Tissue Engineering and Cell - Based Therapies
5. Liver tissue engineering: successes and limitationsp. 57
6. Pancreatic islet and stem cell transplantation in diabetes mellitus: results and perspectivesp. 69
7. Cell based therapy of chronic degenerative diseases of the central nervous systemp. 97
8. CD 34+ cells in hematopoietic stem cell transplantationp. 107
9. The effects of different growth factors on human bone marrow stromal cells differentiating into hepatocyte-like cellsp. 119
III. Biomarkers for Tissue-Engineered Products
10. Oxidative DNA damage biomarkers used in tissue-engineered skinp. 129
11. Biomarkers used to detect genetic damage in tissue-engineered skinp. 137
IV. Biomaterials in Tissue Engineering and Repair
12. Design peptide scaffolds for regenerative medicinep. 147
13. Progresses in synthetic vascular prostheses: toward the endothelializationp. 165
14. Adhesion and growth of rat aortic smooth muscle cells on lactide-based polymersp. 179
15. Biodegradable copolymers carrying cell-adhesion peptide sequencesp. 191
16. Polymer based scaffolds and carriers for bioactive agents from different natural origin materialsp. 201
17. Preparation and characterization of natural/synthetic hybrid scaffoldsp. 235
18. Polyhipe polymer: a novel scaffold for in vitro bone tissue engineeringp. 247
19. Pancreatic islet culture and transplantation using chitosan and PLGA scaffoldsp. 255
V. Gene Therapy and Other Approaches
20. Challenges and prospects for targeted transgenesis in livestockp. 265
21. Controlled release of bioactive agents in gene therapy and tissue engineeringp. 279
22. Interleukin 1 (IL-1) induces the activation of stat3p. 297
23. The use of antibodies in diagnosis and therapy of cancerp. 309
24. Detection of phage displayed peptides with blocking ability in vascular endothelial growth factor (VEGF) modelp. 327
25. Indexp. 335
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