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Cover image for Neurobiology of body fluid homeostasis : transduction and integration
Title:
Neurobiology of body fluid homeostasis : transduction and integration
Series:
Frontiers in neuroscience

Frontiers in neuroscience (Boca Raton, Fla.)
Physical Description:
xvi, 320 pages : illustrations (some color) ; 25 cm.
ISBN:
9781466506930
Abstract:
"The importance of the regulation of salt is of clinical relevance given its relation to the "epidemic" of high blood pressure and that virtually all foods throughout the EU and USA will be mandated to reduce their salt content. This book covers virtually all aspects of the innate drives of thirst and salt, including transduction, sensory mechanism, afferent systems, organization, CNS integrative circuitry, and efferent pathways and effectors systems. It also covers the addition aspects of salt appetites and the orexigenic aspects, as well as other emerging topics in this field"--Provided by publisher.

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32050000000293 QP535.N2 N48 2014 Open Access Book Book
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Summary

Summary

A timely symposium entitled Body-Fluid Homeostasis: Transduction and Integration was held at Araraquara, São Paulo, Brazil in 2011. This meeting was convened as an official satellite of a joint gathering of the International Society for Autonomic Neuroscience (ISAN) and the American Autonomic Society (AAS) held in Buzios, Rio de Janeiro. Broad international participation at this event generated stimulating discussion among the invited speakers, leading to the publication of Neurobiology of Body Fluid Homeostasis: Transduction and Integration.

Drawn from the proceedings and filled with rich examples of integrative neurobiology and regulatory physiology, this volume:







Provides updated research using human and animal models for the control of bodily fluids, thirst, and salt appetite

Explores neural and endocrine control of body fluid balance, arterial pressure, thermoregulation, and ingestive behavior

Discusses recent developments in molecular genetics, cell biology, and behavioral plasticity

Reviews key aspects of brain serotonin and steroid and peptide control of fluid consumption and arterial pressure



The book highlights research conducted by leading scientists on signal transduction and sensory afferent mechanisms, molecular genetics, perinatal and adult long-term influences on regulation, central neural integrative circuitry, and autonomic/neuroendocrine effector systems. The findings discussed by the learned contributors are relevant for a basic understanding of disorders such as heat injury, hypertension, and excess salt intake. A unique reference on the neurobiology of body fluid homeostasis, this volume is certain to fuel additional research and stimulate further debate on the topic.


Author Notes

Laurival Antonio De Luca, José Vanderlei Menani, Alan Kim Johnson


Table of Contents

Micah LeshemAlastair V. FergusonJosé Antunes-Rodrigues and Silvia G. Ruginsk and André S. Mecawi and Lisandra O. Margatho and Wagner L. Reis and Renato R. Ventura and Andréia L. da Silva and Tatiane Vilhena-Franco and Lucila L. K. EliasJosé Vanderlei Menani and Alexandre A. Vieira and Débora S. A. Colombari and Patrícia M. De Paula and Eduardo Colombari and Laurival A. De Luca Jr.Derek DanielsGina L. C. Yosten and Willis K. SamsonMichael J. McKinley and Michael L. MathaiOsmolality and Gustavo R. Pedrino and Daniel A. Rosa and Oswaldo U. Lopes and Sergio L. CravoLaura Vivas and Andrea Godino and Carolina Dalmasso and Ximena E. Caeiro and Ana F. Macchione and Maria J. CambiassoJosmara B. Fregoneze and Hilda S. Ferreira and Carla Patricia N. LuzAndré S. Mecawi and Fabricia V. Fonseca and Iracema G. de Araujo and Luis C. ReisWolfgang LiedtkeCaiping Mao and Lijun Shi and Na Li and Feichao Xu and Zhice XuSeth W. Hurley and Robert L. Thunhorst and Alan Kim JohnsonLaurival A. De Luca Jr. and Richard B. David and José V. Menani
Prefacep. ix
Editorsp. xi
Contributorsp. xiii
Chapter 1 The Human Penchant for Deranged Salt Balancep. 1
Chapter 2 Circumventricular Organs: Integrators of Circulating Signals Controlling Hydration, Energy Balance, and Immune Functionp. 23
Chapter 3 Neuroendocrinology of Hydromineral Homeostasisp. 37
Chapter 4 Preoptic-Periventricular Integrative Mechanisms Involved in Behavior, Fluid-Electrolyte Balance, and Pressor Responsesp. 67
Chapter 5 Diverse Roles of Angiotensin Receptor Intracellular Signaling Pathways in the Control of Water and Salt Intakep. 89
Chapter 6 Separating Thirst from Hungerp. 103
Chapter 7 Interdependent Preoptic Osmoregulatory and Thermoregulatory Mechanisms Influencing Body Fluid Balance and Heat Defensep. 111
Chapter 8 Catecholaminergic Medullary Pathways and Cardiovascular Responses to Expanded Circulating Volume and Increasedp. 123
Chapter 9 Neurochemical Circuits Subserving Fluid Balance and Baroreflex: A Role for Serotonin, Oxytocin, and Gonadal Steroidsp. 141
Chapter 10 Brain Serotonergic Receptors and Control of Fluid Intake and Cardiovascular Function in Ratsp. 167
Chapter 11 Serotonergic Autoinhibition within Dorsal Raphe Nucleus Modulates Sodium Appetitep. 197
Chapter 12 A Classic Innate Behavior, Sodium Appetite, Is Driven by Hypothalamic Gene-Regulatory Programs Previously Linked to Addiction and Rewardp. 215
Chapter 13 Development of Local RAS in Cardiovascular/Body Fluid Regulatory Systems and Hypertension in Fetal Originsp. 223
Chapter 14 Sodium Appetite Sensitizationp. 279
Chapter 15 Homeostasis and Body Fluid Regulation: An End Notep. 303
Indexp. 311
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