Biodegradable Polymers in Clinical Use and Clinical Development

Title:

Publication Information:

Hoboken, NJ : Wiley, 2011

Physical Description:

xv, 734 p. : ill. ; 24 cm.

ISBN:

9780470424759

General Note:

Includes index

Abstract:

"This book focuses on biodegradable polymers that are already in clinical use or under clinical development. Synthetic and natural polymers will be included. This excludes polymers that have been investigated and did not reach clinical development. The purpose of this book is to provide updated status of the polymers that are clinical use and those that are now being developed for clinical use and hopefully will reach the clinic during the next 5 years. The book provides information that of interest to academics and practicing researchers including chemists, biologists and bioengineers and users: physicians, pharmacists"-- Provided by publisher.

"This book will focus on biodegradable polymers that are already in clinical use or under clinical development"-- Provided by publisher.

Subject Term:

Polymers in medicine

Biodegradable plastics

Added Author:

Domb, A. J. (Abraham J.)

Kumar, Neeraj

Ezra, Aviva

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Library	Item Barcode	Call Number	Material Type	Item Category 1	Status
Searching... PSZ JB	30000010251524	R857.P6 B567 2011	Open Access Book	Book	Searching... Unknown

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Summary

This book focuses on biodegradable polymers that are already in clinical use or under clinical development. Synthetic and natural polymers will be included. This excludes polymers that have been investigated and did not reach clinical development.

The purpose of this book is to provide updated status of the polymers that are clinical use and those that are now being developed for clinical use and hopefully will reach the clinic during the next 5 years. The book provides information that of interest to academics and practicing researchers including chemists, biologists and bioengineers and users: physicians, pharmacists.

Author Notes

Abraham J. Domb is professor of Medicinal Chemistry and natural Products at the School of Pharmacy, the Hebrew University. Following time at Syntex Research in California, and MIT/Harvard as a research associate, he founded and headed the Drug Delivery and Polymer division at Nova Pharmaceuticals in Baltimore. Dr. Domb's primary research interests are in biopolymers, gene therapy, controlled drug delivery, cancer therapy, biodegradable polymers, hydrogels, coating of medical devices, nanoparticulate systems, and polymeric complexes.
Neeraj Kumar is Assistant Professor of Pharmaceutics at the National Institute of Pharmaceutical Educational Research (NIPER), India, He Obtained his PhD at the Indian Institute of Technology, Roorkee, India, Before being appointed as Lady Davis Postdoctoral Fellow at the Hebrew University of Jerusalem. Dr. Kumar's current interests are in biomaterials, tissue engineering, drug delivery, and hydrogels.
Aviva Ezra is a researcher at the Institute of Drug Research, School of Pharmacy, The Hebrew University of Jerusalem. She earned her PhD in pharmaceutics from the School of Pharmacy. Dr. Ezra's research interests include pharmaceutics, drug delivery systems, and pharmaceutical analysis.

Jay Prakash Jain and Wubante Yenet and Abraham J. Domb and Neeraj KumarWahid Khan and Deepak Yadav and Abraham J. Domb and Neeraj KumarAnuradha Subramanian and Kirthanashri Srinivasan Vasanthan and Uma Maheswari Krishnan and Swaminathan SethuramanUdi Nussinovitch and Amos NussinovitchRamu Parthasarathi and Athipettah JayakrishnanRajendra P. Pawar and Babasaheb A. Kushekar and Bhaskar S. Jadhav and Kiran R. Kharat and Ravikumer M. Borade and Abraham J. DombKesaven Bhubalan and Wing-Hin Lee and Kumar SudeshKevin Letchford and Anders Sodergard and David Plackett and Samuel Gilchrist and Helen BurtRavikumar M. Borade and Abrahan J. Domb and Archana A. Sawale and Rajendra P. Pawar and Kiran R. KharatKevin Cooper and Aruna Nathan and Murty VyakarnamRajendra P. Pawar and Ashok E. Jadhav and Sumangala B. Tathe and Bhimrao C. Khade and Abraham J. DombTeerapol Srichana and Tan SuwandechaQing Lv and Kevin W.-H. Lo and Lakshmi S. Nair and Cato T. LaurencinJeff Sparks and Khursheed AnwerShalini Verma and Kalpna Garkhal and Anupama Mittal and Neeraj KumarShimon A. Unterman and Noman A. Marcus and Jennifer H. ElisseeffParikshit Bansal and Shalini Verma and Wahid Khan and Neeraj Kumar

Contributors	p. ix
Preface	p. xiii
Part I General	p. 1
1 Biodegradable Polymers in Drug Delivery	p. 3
Part II Blodegradable polymers of Natural Origin: Protein-Based Polymers	p. 59
2 Collagen	p. 61
3 Properties and Hemostatic Application of GelatinJalinder Totre and Diana lckowicz and Abraham J. Domb
Part III Biodegradable Polymers of Natural Origin: Polysaccharides	p. 111
4 Chitosan and its Derivatives in Clinical Use and Applications	p. 113
5 Clinical Uses of Alginate	p. 137
6 Dextran and Pentosan Sulfate - Clinical Applications	p. 185
7 Arabinogalactan in Clinical Use	p. 217
Part IV Boldegradable Polymers of Natural Origin: Polyesters	p. 247
8 Polyhydroxyalkanoate	p. 249
Part V Synthetic Bodegradable polymers	p. 317
9 Lactide and Glycolide Polymers	p. 319
10 Polyanhydrides-Poly(CPP-SA), Fatty-Acid-Based Polyanhydrides	p. 367
11 Poly(e-Caprolactone-co-Glycolide): Biomedical Applications of a Unique Elastomer	p. 401
12 Medicinal Applications of Cyanoacrylate	p. 417
13 Polyethylene Glycol in Clinical Application and PEGylated Drugs	p. 451
Part VI Inorganic Polymers	p. 495
14 Calcium-Phosphate-Based Ceramics for Biomedical Applications	p. 497
Part VII Blodegradable Polymers for Emerging Clinical Uses	p. 519
15 Biocompatible Polymers for Nucleic Acid Delivery	p. 521
16 Biodegradable Polymers for Emerging Clinical Use in Tissue Engineering	p. 565
17 Injectable Polymers	p. 631
Part VIII IPR Aspects of Bodegradable polymers	p. 665
18 Global Patent and Technological Status of Biodegradable Polymers in Drug Delivery and Engineering	p. 667
Index	p. 727

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Summary

Summary

Author Notes

Table of Contents