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Library | Item Barcode | Call Number | Material Type | Item Category 1 | Status |
|---|---|---|---|---|---|
Searching... | 35000000000196 | QH505 P455 2013 f | Open Access Book | Folio Book | Searching... |
Searching... | 30000010311922 | QH505 P455 2013 f | Open Access Book | Book | Searching... |
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Summary
Summary
Physical Biology of the Cell is a textbook for a first course in physical biology or biophysics for undergraduate or graduate students. It maps the huge and complex landscape of cell and molecular biology from the distinct perspective of physical biology. As a key organizing principle, the proximity of topics is based on the physical concepts that unite a given set of biological phenomena. Herein lies the central premise: that the appropriate application of a few fundamental physical models can serve as the foundation of whole bodies of quantitative biological intuition, useful across a wide range of biological problems. The Second Edition features full-color illustrations throughout, two new chapters, a significantly expanded set of end-of-chapter problems, and is available in a variety of e-book formats.
Author Notes
Rob Phillips is the Fred and Nancy Morris Professor of Biophysics and Biology at the California Institute of Technology. He received a PhD in Physics from Washington University in St. Louis.
Jane Kondev is a Professor of Physics in the Graduate Program in Quantitative Biology at Brandeis University. He received his Physics BS degree from the University of Belgrade, and his PhD from Cornell University.
Julie Theriot is a Professor of Biochemistry and of Microbiology and Immunology at the Stanford University School of Medicine. She received concurrent BS degrees in Physics and Biology from the Massachusetts Institute of Technology, and a PhD in Cell Biology from the University of California at San Francisco.
Hernan G. Garcia is an Associate Research Fellow at Princeton University. He received a BS in Physics from the University of Buenos Aires and a PhD in Physics from the California Institute of Technology.
Reviews 1
Choice Review
This upper-level, biophysical course resource signals a shift from emphasizing traditional biophysical topics such as thermodynamics and enzyme kinetics to more topical issues such as single molecule mechanics, molecular bending, and membrane structure. This shift is warranted since the trend in many leading university biophysics programs is to embrace more biologically related problems. This is one of the few books that makes an effort to integrate molecular physiology with modern biophysics. In this 20-chapter work, Phillips (CalTech), Kondev (Brandeis), and Theriot (Stanford Univ. School of Medicine) deal with somewhat simple interactions such as solute-solvent up through quite complex systems involving linked networks. The authors show and discuss actual experimental data, and reduce cellular processes to mathematical expressions whenever possible. A nice feature is that the descriptions of the mathematics used to describe the particular phenomenon are introduced and reviewed separately before being applied to the biological problem. All chapters contain problem sets as well as suggested readings. The time and effort put into this book are readily apparent. This work has some real meat to it and should be adopted by a number of universities. It can also serve as an excellent reference for the individual topics covered. Summing Up: Highly recommended. Upper-division undergraduate through professional collections. J. M. Tomich Kansas State University
Table of Contents
| Part I The Facts of Life |
| 1 Why: Biology by the Numbers |
| 2 What and Where |
| 3 When: Stopwatches at Many Scales |
| 4 Who: "Bless the Little Beasties" |
| Part II Life at Rest |
| 5 Mechanical and Chemical Equilibrium |
| 6 Entropy Rules! |
| 7 Two-State Systems |
| 8 Random Walks and the Structure of Macromolecules |
| 9 Electrostatics for Salty Solutions |
| 10 Beam Theory |
| 11 Biological Membranes |
| Part III Life in Motion |
| 12 The Mathematics of Water |
| 13 A Statistical View of Biological Dynamics |
| 14 Crowded and Disordered Environments |
| 15 Rate Equations and Dynamics in the Cell |
| 16 Dynamics of Molecular Motors |
| 17 Biological Electricity |
| 18 Light and Life |
| Part IV The Meaning of Life |
| 19 Organization of Biological Networks |
| 20 Biological Patterns: Order in Space and Time |
| 21 Sequences, Specificity, and Evolution |
| 22 Whither Physical Biology? |
