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Summary
Summary
The Encyclopedia of Spectroscopy and Spectrometry provides authoritative and comprehensive coverage of the whole topic of spectroscopy, from theory to applications. Short articles, each covering one aspect of spectroscopy, provide the professional spectroscopist working in academia or industry with the essential facts and background on areas of spectroscopy peripheral to their own. A list of further reading at the end of each article directs the reader to the level of detail required for professional purposes. Articles are arranged alphabetically, each having been named to facilitate logical access by the reader. Each article is flagged as to which area of spectroscopy it covers ("Mass Spectroscopy," "Magnetic Resonance," etc.) and whether it covers theory, methods and instrumentation, or applications. Users can refer to an alphabetical article listing, or to a listing arranged according to subject area to locate articles. Further reading lists at the end of each article allow easy access to the primary literature. Extensive cross-referencing, a complete subject index, numerous figures, and color plates are included in each volume. Initial access to the online version offering extensive hypertext linking and advanced search tools is available to buyers of the print edition. Ongoing access is maintained for a minimum annual fee.
Author Notes
John Lindon is a Professor and Senior Research Investigator in the Division of Computational and Systems Medicine, part of the Department of Surgery and Cancer, Imperial College London, UK. He is also a founder Director of, and a Consultant to, Metabometrix Ltd, a company spun out of Imperial College to exploit the commercial possibilities of metabolic phenotyping.
He obtained his B.Sc (1966), Ph.D. (1969) and D.Sc (1993) degrees from Birmingham University UK. He was a postdoctoral fellow at Columbia University, New York, USA (1969-1970), and then joined the Chemistry Department of Southampton University UK, to use NMR methods to research the properties of liquid crystals and later as a faculty member. From 1976 to 1995 he was at the Wellcome Research Laboratories (a pharmaceutical company) in the UK, occupying several senior scientific and managerial roles related to the use of physical chemical methods in drug design and discovery, latterly as Head of Spectroscopy, until they were taken over by Glaxo, now part of GlaxoSmithKline in 1995. He then joined Birkbeck College, University of London and moved to Imperial College London as part of the transfer of the Jeremy Nicholson team in 1998.
He has co-authored a book on NMR of oriented molecules, another on metabonomics in toxicology, one on metabonomics in general, one on NMR in pharmaceutical &D and one on metabolic phenotyping in personalised medicine and population screening. He is Editor-in-Chief of the Encyclopedia of Spectroscopy and Spectrometry with a third edition in preparation, is on the editorial board of a number of journals and has authored many review articles and chapters, plus more than 450 research papers. He has given many key-note, plenary and invited lectures around the world.
His major research interest is the use of NMR and other analytical methods coupled with multivariate statistics to study biofluids and tissues, a field now termed metabolic phenotyping, leading to new approaches for disease diagnosis, prediction of outcomes and assessing disease risks in populations. His other achievements include the pioneering of a range of NMR data acquisition and processing methods, the use of nematic liquid crystals and NMR spectroscopy for determing accurate molecular structures in the liquid state, and the application of spectroscopy and other physical chemistry methods in drug design. Developments of NMR-based approaches in biomedical research include the use of directly-coupled HPLC-NMR fo mixture analysis and application of high resolution magic-angle-spinning NMR to tissue samples.
Reviews 1
Choice Review
This opus of more than 3,300 pages covers an extraordinary range of topics relating to spectroscopy and mass spectrometry. Editors Lindon, Tranter, and Koppenaal are specialists in biological NMR spectroscopy, chiral analytical methods, and atomic mass spectrometry, respectively. This edition represents a major update; though the majority of entries are reprinted verbatim from the first edition (CH, Dec'00, 38-2171; edited by Lindon, Tranter, and J. L. Holmes), the second edition features many new entries focused mainly on technologies that emerged in the last decade. These include proteomics and NMR studies on biofluids. Entries in the encyclopedia are classified as theory, methods/instrumentation, applications, historical perspectives, or overviews and are written in the style of a review journal article, ranging from about 5 to 15 pages. Clearly written and containing numerous figures (some in full color), tables, and extensive references, entries are mostly understandable to a typical working chemist, though a minority are quite specialized. The alphabetical arrangement is usable, but a subject-based arrangement might be more convenient for researching related topics.This encyclopedia is unique in its scope and depth. It aims to assemble a comprehensive, balanced collection of information about both established and cutting-edge spectroscopic and spectrometric science, covering theoretical and practical aspects while maintaining readability and accessibility. Inevitably, in such an ambitious work, some important topics in rapidly evolving fields will be overlooked; e.g., little mention is made of the electron-transfer dissociation technique in mass spectrometry. Entries reprinted from the first edition were not updated at all. While newer entries often bring the information up to date, some of the older entries remain outdated, particularly in their bibliographies. Overall, this encyclopedia gathers vast amounts of information into a single work. Though imperfect, it is useful for working chemists and for others, including advanced students, as a reference in spectroscopy and spectrometry from ATR to Zeeman. Summing Up: Recommended. Upper-division undergraduates through professionals/practitioners. E. J. Chang York College
Table of Contents
| Atmospheric Pressure Ionisation in Mass Spectrometry |
| Atomic Absorption, Methods & Instrumentation |
| Atomic Absorption, Theory |
| Atomic Emission and Fluorescence, Theory |
| Atomic Emission, Methods & Instrumentation |
| Atomic Fluorescence, Methods & Instrumentation |
| Atomic Spectroscopy, Historical Perspective |
| ATR and Reflectance IR Spectroscopy, Applications |
| Biochemical Applications of Fluorescence Spectroscopy |
| Biochemical Applications of Mass Spectrometry |
| Biochemical Applications of Raman Spectroscopy |
| Biofluids Studied by NMR |
| Biological Applications of EPR |
| Biological Applications of IR Spectroscopy |
| Biomacromolecular Applications of Circular Dichroism and ORD |
| Biomacromolecular Applications of UV-visible Absorption Spectroscopy |
| Biomedical Applications of Atomic Spectroscopy |
| C13 NMR in Solution, Applications |
| C13 NMR Methods |
| C13 NMR Parameter Survey |
| Calibration and Reference Systems (Regulatory Authorities) |
| Carbohydrates Studied by NMR |
| Cells Studied by NMR |
| Chemical Applications of EPR |
| Chemical Exchange Effects in NMR |
| Chemical Ionisation in Mass Spectrometry |
| Chemical Reactions Studied by Electronic Spectroscopy |
| Chemical Shift and Relaxation Reagents in NMR |
| Chemical Structure Information from Mass Spectrometry |
| Chemical Studies Using IR |
| Chemicals and Solvents, Applications of Atomic Spectroscopy |
| Chiroptical Spectroscopy, Orientated Molecules and Anisotropic Systems |
| Chiroptical Spectroscopy, Emission Theory |
| Chiroptical Spectroscopy, General Theory |
| Chromatography-IR Methods & Instrumentation |
| Chromatography-MS Methods |
| Chromatography-NMR Applications |
| Chromatography-IR Applications |
| CIDNP Applications |
| Circular Dichroism Spectrometers |
| Circularly Polarised Luminescence and Fluorescence Detected Circular Dichroism |
| Cluster Ions Measured Using Mass Spectrometry |
| Colorimeters |
| Colorimetry, Applications |
| Colorimetry, Theory |
| Computational Methods of Analysis and Chemometrics in Near Infrared Spectroscopy |
| Contrast Mechanisms in MRI |
| Cosmochemical Applications Using Mass Spectrometry |
| Crystals and Polymers, Theory and Prediction of Vibrational Spectra |
| Diffusion Studied Using NMR Spectroscopy |
| Drug Metabolism Studied Using NMR Spectroscopy |
| Dyes and Indicators, Applications of UV-visible Absorption Spectroscopy |
| Electromagnetic Radiation |
| Electron Diffraction, Applications |
| Electron Diffraction, Instrumentation |
| Electron Microscope Applications |
| Electron Microscope Instrumentation |
| Electron Microscope Theory |
| Electronic Absorption Spectroscopy, Theory |
| Electronic Absorption, Spectrometers |
| Electronic Components, Applications of Atomic Spectroscopy |
| Electronic Emission & Fluorescence Spectroscopy, Theory |
| Electronic Spectroscopy, Historical Perspective |
| Electronic Spectroscopy, Linear Dichroism, Theory |
| Electrospray Ionisation in Mass Spectrometry |
| Ellipsometry, Technique and Applications |
| Enantiomeric Purity Studied Using NMR |
| Energy Transfer in Transition Metal & Lanthanide Systems |
| Environmental & Agricultural Applications of Atomic Spectroscopy |
| Environmental Applications of Electronic Spectroscopy |
| Environmental Applications of IR Spectroscopy |
| Environmental Applications of Mass Spectrometry |
| EPR Imaging |
| EPR Methods |
| EPR Spectroscopy, Theory |
| Exciton Coupling |
| F19 NMR Applications (Solution State) |
| Far Infrared Spectroscopy Applications |
| Fast Atom Bombardment Ionisation in Mass Spectrometry |
| Fibre Optics |
| Fibres and Films Studied Using X-ray Diffraction |
| Field Desorption and Field Ionisation in Mass Spectrometry |
| Field Ionisation Kinetics in Mass Spectrometry |
| Flame and Temperature Measurement Using Vibrational Spectroscopy |
| Fluorescence and Emission, Instruments |
| Fluorescence Anisotropy (Static & Dynamic) |
| Fluorescence Lifetime Spectroscopy, Applications |
| Fluorescence Microscopy, Applications |
| Fluorescent Molecular Probes |
| Food & Dairy Products, Applications of Atomic Spectroscopy |
| Food Science Applications of Mass Spectrometry |
| Food Science Applications of NMR Spectroscopy |
| F |
