The diabetic foot

It has been more than 4 years since the first edition of The Diabetic Foot was published. Over this period of time, it has become absolutely clear that diabetes is becoming a pandemic that challenges the health care resources of all societies, from the developing ones to the most advanced. It is therefore not surprising that diabetic foot disease is still a major problem and, if anything, is growing in size rather than coming under control. One positive development is that our knowledge of the pathophysiology of foot pr- lems in diabetes has considerably expanded. Furthermore, it has been realized that impairment in wound healing is associated with pathways that are related to the dev- opment of cardiovascular disease, both in the micro- and macrocirculation. In The Diabetic Foot: Second Edition, we have tried to keep the spirit of the first edition, which is to give the interested reader a full view of diabetic foot disease and to emphasize the need for a multidisciplinary approach in its management. As with the first edition, we have relied on the long tradition of the Joslin-Beth Israel Deconess Foot Center, one of the oldest and most experienced diabetic foot centers. We have also tried to emphasize new developments in basic and clinical research that we hope will be translated to clinical practice in the future.

Peter SheehanGayle E. Reiber and Lynne V. McFarlandI. Kelman CohenJeffrey M. Davidson and Luisa DiPietroEric C. Soller and Ioannis V. YannasSolomon TesfayeThanh Dinh and Aristidis VevesChantel Hile and Nikhil Kansal and Allen Hamdan and Frank W. LoGerfoThomas E. Lyons and Barry I. Rosenblum and Aristidis VevesC. H. M. van Schie and A. J. M. BoultonStephanie Wu and David G. Armstrong and Lawrence A. Lavery and Lawrence B. HarklessMary G. Hochman and Yvonne Cheung and David P. Brophy and J. Anthony ParkerAdolf W. KarchmerRobert G. FrykbergVincent FalangaOscar M. Alvarez and Lee Markowitz and Martin WendelkenJohn M. GiuriniRonald A. Sage and Michael Pinzur and Rodney Stuck and Coleen NapolitanoChristopher E. AttingerDavid L. SteedThanh Dinh and Aristidis VevesKakra Hughes and David Campbell and Frank B. Pomposelli, Jr.Sherry D. ScovellKatie Weinger and Arlene SmaldoneLuigi Uccioli

Preface	p. v
Contributors	p. ix
1 Introduction to Diabetes: Principles of Care in the Surgical Patient With Diabetes	p. 1
2 Epidemiology and Health Care Costs for Diabetic Foot Problems	p. 39
3 The Evolution of Wound Healing: From Art to Science	p. 51
4 The Wound-Healing Process	p. 59
5 Induced Regeneration of Skin and Peripheral Nerves	p. 83
6 Diabetic Neuropathy	p. 105
7 Microvascular Changes in the Diabetic Foot	p. 131
8 Clinical Features and Diagnosis of Macrovascular Disease	p. 147
9 Foot Pressure Abnormalities in the Diabetic Foot	p. 163
10 Biomechanics of the Diabetic Foot: The Road to Foot Ulceration	p. 185
11 Clinical Examination of the Diabetic Foot and the Identification of the At-Risk Patient	p. 201
12 Imaging of the Diabetic Foot	p. 227
13 Microbiology and Treatment of Diabetic Foot Infections	p. 255
14 Charcot Arthropathy in the Diabetic Foot	p. 299
15 Preparation of the Wound Bed of the Diabetic Foot Ulcer	p. 269
16 Local Care of Diabetic Foot Ulcers: Assessment, Dressings, and Topical Treatments	p. 311
17 Surgical Treatment of the Ulcerated Foot	p. 335
18 Amputation and Rehabilitation of the Diabetic Foot	p. 363
19 Soft Tissue Reconstructive Options for the Ulcerated or Gangrenous Diabetic Foot	p. 391
20 Role of Growth Factors in the Treatment of Diabetic Foot Ulceration	p. 447
21 Living Skin Equivalents for the Diabetic Foot Ulcer	p. 459
22 Lower Extremity Arterial Reconstruction in Patients With Diabetes Mellitus: Principles of Treatment	p. 473
23 Angioplasty and Other Noninvasive Vascular Surgical Procedures	p. 493
24 Psychosocial and Educational Implications of Diabetic Foot Complications	p. 507
25 The Role of Footwear in the Prevention of Diabetic Foot Problems	p. 523
Index	p. 543

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