Brain repair after stroke

Title:

Publication Information:

Cambridge, ENK. : New York : Cambridge University Press, 2010.

Physical Description:

x, 292 p. : ill. (some col.) ; 26 cm.

ISBN:

9780521515337

Subject Term:

Cerebrovascular disease -- Patients -- Rehabilitation

Brain -- Regeneration

Brain damage -- Treatment

Added Author:

Cramer, Steven C.

Nudo, Randolph J.

Available:*

Library	Item Barcode	Call Number	Material Type	Item Category 1	Status
Searching... PSZ JB	30000010273999	RC388.5 B732 2010	Open Access Book	Book	Searching... Unknown

Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.

Author Notes

Steven C. Cramer is Associate Professor, Departments of Neurology and Anatomy and Neurobiology, University of California, Irvine, CA, USA.
Randolph J. Nudo is professor, Department of Molecular and integrative Physiology, and Director of the Landon center on Aging, University of Kansas Medical center, Kansas City, KS, USA.

Jeffrey A. Kleim and Susan SchwerinS. Thomas CarmichaelTheresa A. Jones and DeAnna L. AdkinsG. Campbell Teskey and Bryan KolbBarbro B. JohanssonMaurits P. A. van Meer and Rick M. DijkhuizenRandolph J. NudoJ. Leigh Leasure and Andreas Luft and Timothy SchallertRüdiger J. SeitzP. Talelli and O. Swayne and J. C. RothwellNick S. WardCornelius Weiller and Dorothee SaurAlex R. Carter and Gordon L. Shulman and Maurizio CorbettaThomas PlatzSamir Belagaje and Brett KisselaSteven C. CramerIsabelle Loubinoux and François CholletDavid J. ReinkensmeyerGottfried Schlaug and Leonardo G. CohenSteven L. Wolf and Carolee J. WinsteinValerie M. Pomeroy and Stephen J. Page and Megan FarrellJohn Chae and Leigh R. HochbergSeth P. Finklestein and JingMei RenYi Li and Michael Chopp

Preface	p. vii
List of contributors	p. viii
Section I Basic Science and Animal Studies
1 Motor map plasticity: a neural substrate for improving motor function after stroke	p. 1
2 Molecular mechanisms of neural repair after stroke	p. 11
3 Behavioral influences on neuronal events after stroke	p. 23
4 Post-stroke recovery therapies in animals	p. 35
5 Environmental effects on functional outcome after stroke	p. 47
6 Functional and structural MR imaging of brain reorganization after stroke	p. 57
7 Stroke recovery in non-human primates: a comparative perspective	p. 67
8 Issues in translating stroke recovery research from animals to humans	p. 77
Section II Spontaneous Stroke Recovery in Humans
9 Brain events in the acute period of stroke in relation to subsequent repair	p. 87
10 Changes in cortical excitability and interhemispheric interactions after stroke	p. 103
11 Human brain mapping of the motor system after stroke	p. 113
12 Recovery from aphasia: lessons from imaging studies	p. 125
13 Brain mapping of attention and neglect after stroke	p. 133
14 Depression and its effects after stroke	p. 145
15 Epidemiology of stroke recovery	p. 163
Section III Treatment Strategies
16 Issues in clinical trial methodology for brain repair after stroke	p. 173
17 Neuropharmacology in stroke recovery	p. 183
18 Robotic approaches to stroke recovery	p. 195
19 Electromagnetic approaches to stroke recovery	p. 207
20 Intensive physical therapeutic approaches to stroke recovery	p. 219
21 Cognitive approaches to stroke recovery	p. 233
22 Electrical stimulation approaches to stroke recovery	p. 247
23 Growth factors as treatments for stroke	p. 259
24 Cellular approaches to stroke recovery	p. 267
Index	p. 275

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Summary

Summary

Author Notes

Table of Contents