Protein arrays, biochips and proteomics : the next phase of genomic discovery

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New York, NY : Marcel Dekker, 2003

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9780824743123

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Library	Item Barcode	Call Number	Material Type	Item Category 1	Status
Searching... PSZ JB	30000004858878	QH506 P764 2003	Open Access Book	Book	Searching... Unknown

From disease marker identification to accelerated drug development, Protein Arrays, Biochips, and Proteomics offers a detailed overview of current and emerging trends in the field of array-based proteomics. This reference focuses on innovations in protein microarrays and biochips, mass spectrometry, high-throughput protein expression, protein-protein interactions, structural proteomics, and the proteomic marketplace for comprehensive understanding of past, present, and future proteomic research. Offering an abundance of figures and charts, the book compiles a wide variety of technologies and applications ranging from functionalized chip surfaces to strategies for protein expression.

Author Notes

Joanna S. Albala, Ian Humphery-Smith

Sam HanashIan Humphery-SmithRoger Ekins and Frederick ChuBrian HaabSteffen Nock and Peter WagnerErik WischerhoffStefan R. SchmidtMichele Gilbert and Todd C. Edwards and Christa Prange and Mike Malfatti and Ian R. McConnell and Joanna S. AlbalaEric T. Fung and Enrique A. DalmassoAnita Saraf and John R. Yates IIIDavid E. Hill and Nicolas Bertin and Marc VidalIngrid Remy and Stephen W. MichnickWuxian Shi and David A. Ostrov and Sue Ellen Gerchman and Jadwiga H. Kycia and F. William Studier and William Edstrom and Anne Bresnick and Joel Ehrlich and John S. Blanchard and Steven C. Almo and Mark R. ChanceLeah B. Shaw and Vassily Hatzimanikatis and Amit Mehra and Kelvin H. LeeSteven Bodovitz and Julianne Dunphy and Felicia M. Gentile

Foreword	p. iii
Preface	p. v
Contributors	p. xi
1. Protein Biochips and Array-Based Proteomics	p. 1
2. Ultrasensitive Microarray-Based Ligand Assay Technology	p. 81
3. Practical Approaches to Protein Microarrays	p. 127
4. Protein Biochips: Powerful New Tools to Unravel the Complexity of Proteomics?	p. 145
5. Functionalized Surfaces for Protein Microarrays: State of the Art, Challenges, and Perspectives	p. 159
6. High-Throughput Protein Expression, Purification, and Characterization Technologies	p. 173
7. Miniaturized Protein Production for Proteomics	p. 203
8. Protein Profiling: Proteomes and Subproteomes	p. 217
9. Shotgun Proteomics and Its Applications to the Yeast Proteome	p. 233
10. Forward and Reverse Proteomics: It Takes Two (or More) to Tango	p. 255
11. Dynamic Visualization of Expressed Gene Networks	p. 277
12. High-Throughput Structural Biology and Proteomics	p. 299
13. Integration of Proteomic, Genechip, and DNA Sequence Data	p. 325
14. The Proteomics Market	p. 337
Index	p. 351

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Table of Contents