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Library | Item Barcode | Call Number | Material Type | Item Category 1 | Status |
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Summary
Summary
A Practical Guide to Supramolecular Chemistry is an introductory manual of practical experiments for chemists with little or no prior experience of supramolecular chemistry. Syntheses are clearly presented to facilitate the preparation of acyclic and macrocyclic compounds frequently encountered in supramolecular chemistry using straightforward experimental procedures.
Many of the compounds can be used to illustrate classic supramolecular phenomena, for which clear directions are given, or may be developed further as part of the reader's own research. The book also describes techniques commonly used in the analysis of supramolecular behaviour, including computational methods, with many detailed examples.
An invaluable reference for students and researchers in the field embarking on supramolecular chemistry projects and looking for a 'tried and tested' route into the chemistry of key compounds.
An introductory guide to practical syntheses focusing on supramolecular chemistry.
Fully referenced introductions explain the historical and contemporary importance of each compound
Supplementary website including 3D molecular structures, FAQ's about syntheses and suggestions for further experiments
Author Notes
Dr Peter J. Cragg , School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK
Reviews 1
Choice Review
Cragg (Univ. of Brighton, UK) means his book to be an introduction to supramolecular experimental chemistry. Although it does contain some theory and historical background, its primary thrust is to offer chemists who are new to supramolecular chemistry practical syntheses for compounds such as crown ethers, podands, resorcinarenes, and calixarenes. The syntheses use straightforward experimental procedures and equipment normally found in most college and university laboratories. As a guide for the laboratory worker, approximate yields to be expected are given, melting points are listed, and appropriate spectrometric data are recorded (infrared and 1H nuclear magnetic resonance data). Each section and procedure is referenced. Cragg indicates the experiments were repeated and spectra recorded in his laboratory, so the experiments are "tried and tested." ^BSumming Up: Recommended. Upper-division undergraduates through faculty. J. Landesberg Adelphi University
Table of Contents
| Preface | p. ix |
| Introduction | p. 1 |
| 1 Linear components for supramolecular networks | p. 9 |
| 1.1 Flexible components | p. 9 |
| 1.2 Rigid components from Schiff bases | p. 17 |
| 1.3 Flexible tripods | p. 19 |
| 1.4 Simple anion hosts | p. 23 |
| 1.5 Rigid platforms | p. 30 |
| 2 Cyclic synthons | p. 35 |
| 2.1 Planar macrocycles from nature | p. 35 |
| 2.2 Artificial planar macrocycles - phthalocyanines and other cyclic systems | p. 37 |
| 2.3 Serendipitous macrocycles | p. 43 |
| 2.4 Adding functionality to the crowns | p. 46 |
| 2.5 Azacrowns with sidearms | p. 51 |
| 2.6 Water-soluble macrocycles | p. 55 |
| 2.7 Catenanes and rotaxanes | p. 60 |
| 3 Molecular baskets, chalices and cages | p. 69 |
| 3.1 One for beginners | p. 69 |
| 3.2 Calixarenes - essential supramolecular synthons | p. 71 |
| 3.3 Adding lower rim functionality to the calixarenes | p. 77 |
| 3.4 Adding upper rim functionality to the calixarenes | p. 80 |
| 3.5 Oxacalix[3]arenes | p. 84 |
| 3.6 Oxacalixarene derivatives | p. 91 |
| 3.7 Azacalix[3]arenes | p. 99 |
| 3.8 Calixarene variations | p. 102 |
| 3.9 Molecular cages for cations and anions | p. 107 |
| 4 Supramolecular assembly | p. 115 |
| 4.1 Detection, measurement, prediction and visualization | p. 115 |
| 4.2 X-ray crystallography | p. 115 |
| 4.3 Spectroscopic and spectrometric techniques | p. 120 |
| 4.4 Binding constant determination | p. 122 |
| 4.5 Solid state vs. solution behaviour | p. 127 |
| 4.6 Supramolecular chemistry in silico: molecular modelling and associated techniques | p. 127 |
| 4.7 Computational approaches | p. 129 |
| 4.8 A protocol for supramolecular computational chemistry | p. 141 |
| 4.9 Examples of in silico supramolecular chemistry | p. 142 |
| 5 Supramolecular phenomena | p. 161 |
| 5.1 Clathrates | p. 151 |
| 5.2 Stabilization of cation-anion pairs by crown ethers: liquid clathrates | p. 162 |
| 5.3 Receptors for the ammonium ion | p. 168 |
| 5.4 Purification of fullerenes | p. 170 |
| 5.5 Making molecular boxes and capsules | p. 172 |
| 5.6 Self-complementary species and self-replication | p. 176 |
| Appendix 1 Integrated undergraduate projects | p. 185 |
| Appendix 2 Reagents and solvents | p. 189 |
| Index | p. 197 |
