Cover image for Statistical mechanics of cellular systems and processes
Title:
Statistical mechanics of cellular systems and processes
Publication Information:
Cambridge, UK ; New York : Cambridge University Press, 2009
Physical Description:
xii, 215 p., [4] p. of plates : ill. ; 26 cm.
ISBN:
9780521886086

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30000010236260 QP517.T48 S72 2009 Open Access Book Book
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Summary

Summary

Cells are complex objects, representing a multitude of structures and processes. In order to understand the organization, interaction and hierarchy of these structures and processes, a quantitative understanding is absolutely critical. Traditionally, statistical mechanics-based treatment of biological systems has focused on the molecular level, with larger systems being ignored. This book integrates understanding from the molecular to the cellular and multi-cellular level in a quantitative framework that will benefit a wide audience engaged in biological, biochemical, biophysical and clinical research. It will build new bridges of quantitative understanding that link fundamental physical principles governing cellular structure and function with implications in clinical and biomedical contexts.


Author Notes

Muhammad H. Zaman is an Assistant Professor in the Department of Biomedical Engineering and Institute for Theoretical Chemistry at the University of Texas, Austin, USA.


Table of Contents

Jason K. Cheung and Vincent K. Shen and Jeffrey R. Errington and Thomas M. TruskettL. B. FreundTianyi Yang and Muhammad H. ZamanJin WangAryeh Warmflash and Aaron R. DinnerR. Sinatra and J. Gómez-Gardeñes and Y. Moreno and D. Condorelli and L. M. Floría and V. LatoraJun Sun and Michael W. Deem
List of contributorsp. vii
Prefacep. xi
1 Concentration and crowding effects on protein stability from a coarse-grained modelp. 1
2 Observations on the mechanics of a molecular bond under forcep. 26
3 Statistical thermodynamics of cell-matrix interactionsp. 54
4 Potential landscape theory of cellular networksp. 74
5 Modeling gene regulatory networks for cell fate specificationp. 121
6 Structural and dynamical properties of cellular and regulatory networksp. 155
7 Statistical mechanics of the immune response to vaccinesp. 177
Indexp. 214