Cover image for Standards of mouse model phenotyping
Title:
Standards of mouse model phenotyping
Publication Information:
Weinheim : Wiley-VCH, 2006
ISBN:
9783527310319

Available:*

Library
Item Barcode
Call Number
Material Type
Item Category 1
Status
Searching...
30000010105657 QH470.M52 S72 2006 Open Access Book Book
Searching...

On Order

Summary

Summary

This is the first book in the field of mouse genetics to provide comprehensive and standardized methods for the characterization of laboratory mice. The editor is Director of the German Mouse Clinic and member of the Project Committee of the German National Genome Research Network and provides here a brief introduction to the mouse as a model for diseases and functional analysis of genes and proteins. Throughout, he focuses on the characterization of mouse models using the latest phenotyping methods, with the different areas presented in a clearly structured and easily accessible manner.


Author Notes

Dr Hrabe de Angelis is Director if theInstitute of Experimental Genetics, in Munich, Germany and Director of the European Mouse Mutant Archive (EMMA), in Monterotondo, Italy. He is also cofounder of "INGENIUM Biopharmaceuticals AG".

Processor Pierre Chambon is the director of the Institute of Genetics, Molecular and Cell Biology in Strasbourg. He has won numerous scientific prizes including the CNRS Gold Medal and the Grand Prix of the Foundation of Medical Reseach.

Professor Steve Brown is Director of the Mammalian Genetics Unit of the MRC in Harwell, UK, and is a member of EMBO.


Table of Contents

Introduction Generation of mouse models
Phenotyping areas
Endocrinologic anomalies
Metabolic analysis Neurologic disorders Immunology/Allergy Lung function
Nociceptive features Eye disorders
Molecular phenotyping Cardio-vascular disorders
Host-pathogen interactions