Cover image for Colloids in drug delivery
Title:
Colloids in drug delivery
Series:
Surfactant science series ; v. 148

Surfactant science series ; v. 148.
Publication Information:
Boca Raton, FL : CRC Press/Taylor & Francis, 2010
Physical Description:
xxvi, 626 p. : ill. ; 27 cm.
ISBN:
9781439818251
Abstract:
"Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a number of challenging conditions, allowing researchers to cross barriers that have previously prevented efficient treatment while offering improved and more targeted absorption. Summarizing recent research in the field, Colloids in Drug Delivery assembles the work of 65 of the world's leading colloid scientists who examine the full spectrum of this rapidly emerging science, from pure to applied, most of it drawn from their own experience and research."--BOOK JACKET.
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Summary

Summary

Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a number of challenging conditions, allowing researchers to cross barriers that have previously prevented efficient treatment while offering improved and more targeted absorption. Summarizing recent research in the field, Colloids in Drug Delivery assembles the work of 65 of the world's leading colloid scientists who examine the full spectrum of this rapidly emerging science, from pure to applied, most of it drawn from their own experience and research.

The book begins by examining the basics of surfactant and polymer surface activity and self-assembly, the various types of structures formed by such compounds, and their use in drug delivery and biotechnology. It examines the development of controlled and targeted delivery systems by utilizing the various properties of colloids before moving on to discuss various applications and fields of research.

Topics discussed include:

The use of hard, soft, and macromolecular colloidal drug delivery systems formed by surfactants, polymers, proteins, and lipids Recent advances in procolloidal systems, self-emulsifying drug delivery systems, and aerosol applications to pharmaceutical drug delivery Colloidal nanocarriers for imaging applications and the treatment of dental and periodontal diseases Classification and application of colloidal drug delivery systems in tumor targeting The use of colloids for improved nasal, ocular, vaginal, oral, buccal, gastrointestinal, and colon drug delivery

Examining topics necessary to the critical evaluation of a drug candidate's potential for delivery, the book also describes the preparation, classification, interfacial activity, surface modifications and influence on particle characteristics, drug delivery, and drug targeting. Each chapter in this expansive volume explains why a particular system is used for the intended application, how it is made, and how it behaves.

All those concerned with the research, development, and manufacture of drugs will find this a valuable reference, offering a wealth of research upon which they can build.


Author Notes

Monzer Fanun is a member of the faculty of Science and Technology at Al-Quds University.


Table of Contents

Ambikanandan Misra and Kiruba Florence and Manisha Lalan and Tapan ShahSwarnlata SarafSílvia S. Guterres and Fernanda S. Poletto and Letícia M. Colomé and Renata P. Raffin and Adriana R. PohlmannAnja Graf and Karen Krauel-Göllner and Thomas RadesWitold Musial and Vanja KokolChandana Mohanty and Sarbari Acharya and Sanjeeb K. SahooJatin Khurana and Somnath Singh and Alekha K. DashRita Cortesi and Elisabetta EspositoFigen Tirnaksiz and Seyda Akkus and Nevin CelebiLijiljana Djekic and Marija PrimoracMonzer FanunD. P. Maurya and Yasmin Sultana and M. Abul KalamRakesh Patel and Tanmay N. PatelAnan Yaghmur and Michael RappoltYongzhuo Huang and Faquan Yu and Wenquan LiangFederico Bordi and Cesare Cametti and Simona SennatoPaola Luciani and Debora Berti and Piero BaglioniN. S. Santos-Magalhães and N. P. S. Santos and M. C. B. Lira and M. S. Ferraz and E. C. Pereira and N. H. SilvaHu YangAbdus Samad and Mohammad Tariq and Mohammed Intakhab Alam and M. S. AkhterNazrul IslamJinxiang Xi and P. Worth Longest and Paula J. AndersonNader Kalaji and Nida Sheibat-Othman and Hatem FessiH. Yesim Karasulu and Burcak Karaca and Ercüment KarasuluVandana Patravale and Medha Joshi
Prefacep. xiii
Editorp. xxi
Contributorsp. xxiii
Chapter 1 Surfactants and Block Copolymers in Drug Deliveryp. 1
Chapter 2 Application of Colloidal Properties in Drug Deliveryp. 55
Chapter 3 Polymeric Nanocapsules for Drug Delivery: An Overviewp. 71
Chapter 4 Poly(Alkyl Cyanoacrylate) Nanoparticles for Drug Delivery and Vaccine Developmentp. 99
Chapter 5 Stimuli-Sensitive Polymer Gels for Dermal and Transdermal Drug Delivery and Their Application in the Development of Smart Textile Materialsp. 137
Chapter 6 Micelles: The Multifunctional Nanocarrier for Colloidal Drug Deliveryp. 157
Chapter 7 Multiple Emulsions: An Overview and Pharmaceutical Applicationsp. 177
Chapter 8 Pharmaceutical and Biotechnological Applications of Multiple Emulsionsp. 203
Chapter 9 Nanoemulsions as Drug Delivery Systemsp. 221
Chapter 10 Microemulsion Systems: Application in Delivery of Poorly Soluble Drugsp. 245
Chapter 11 Diclofenac Solubilization in Mixed Nonionic Surfactants Microemulsionsp. 271
Chapter 12 Self-Emulsifying Drug Delivery Systemsp. 299
Chapter 13 Liquid Crystals and Their Application in the Field of Drug Deliveryp. 311
Chapter 14 Liquid Crystalline Nanoparticles as Drug Nanocarriersp. 337
Chapter 15 Niosomal Delivery System for Macromolecular Drugsp. 355
Chapter 16 A New Class of Mesoscopic Aggregates as a Novel Drug Delivery Systemp. 365
Chapter 17 Liposomes and Biomacromolecules: Effects of Preparation Protocol on In Vitro Activityp. 395
Chapter 18 Colloidal Nanocarrier Systems as a Tool for Improving Antimycobacterial and Antitumor Activities and Reducing the Toxicity of Usnic Acidp. 409
Chapter 19 Dendrimers in Drug Deliveryp. 435
Chapter 20 Microsphere: A Novel Drug Delivery Systemp. 455
Chapter 21 Colloids in Aerosol Drug Delivery Systemsp. 479
Chapter 22 Respiratory Aerosol Dynamics with Applications to Pharmaceutical Drug Deliveryp. 501
Chapter 23 Colloidal Carriers for Drug Delivery in Dental Tissue Engineeringp. 527
Chapter 24 Classification and Application of Colloidal Drug Delivery Systems: Passive or Active Tumor Targetingp. 545
Chapter 25 Nanocarriers for Imaging Applicationsp. 563
Indexp. 613