Available:*
Library | Item Barcode | Call Number | Material Type | Item Category 1 | Status |
---|---|---|---|---|---|
Searching... | 30000010236260 | QP517.T48 S72 2009 | Open Access Book | Book | Searching... |
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Summary
Summary
Cells are complex objects, representing a multitude of structures and processes. In order to understand the organization, interaction and hierarchy of these structures and processes, a quantitative understanding is absolutely critical. Traditionally, statistical mechanics-based treatment of biological systems has focused on the molecular level, with larger systems being ignored. This book integrates understanding from the molecular to the cellular and multi-cellular level in a quantitative framework that will benefit a wide audience engaged in biological, biochemical, biophysical and clinical research. It will build new bridges of quantitative understanding that link fundamental physical principles governing cellular structure and function with implications in clinical and biomedical contexts.
Author Notes
Muhammad H. Zaman is an Assistant Professor in the Department of Biomedical Engineering and Institute for Theoretical Chemistry at the University of Texas, Austin, USA.
Table of Contents
List of contributors | p. vii |
Preface | p. xi |
1 Concentration and crowding effects on protein stability from a coarse-grained model | p. 1 |
2 Observations on the mechanics of a molecular bond under force | p. 26 |
3 Statistical thermodynamics of cell-matrix interactions | p. 54 |
4 Potential landscape theory of cellular networks | p. 74 |
5 Modeling gene regulatory networks for cell fate specification | p. 121 |
6 Structural and dynamical properties of cellular and regulatory networks | p. 155 |
7 Statistical mechanics of the immune response to vaccines | p. 177 |
Index | p. 214 |