Cover image for Anatomy ontologies for bioinformatics : principles and practice
Title:
Anatomy ontologies for bioinformatics : principles and practice
Series:
Computational biology ; 6
Publication Information:
London : Springer, 2007
Physical Description:
xvi, 354 p. : ill. ; 24 cm.
ISBN:
9781846288845

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30000010178168 QH324.2 A524 2008 Open Access Book Book
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Summary

Summary

This book is about the ontology of anatomy. With respect to the individual ?elds of ontology and anatomy, the ontology of anatomy has aspects of both an old and a new topic area. A new aspect for anatomy is that the ontology of anatomy brings medicine together with molecular biology and its related subjects. Similarly, for the ?eld of ontology, biomedical informatics has seen an explosion in the use of onto- gies and ontology-like resources. There has been a particular interest in ontologies for human anatomy and also the anatomy of other types of organism. This explosion has pushed the ?eld of ontology into the limelight, with new practical applications of ontology being developed and new formalisms to accommodate the things that biologists need to say. The ontology of anatomy covers a broad spectrum of life sciences, but why should medics and geneticists, molecular biologists, etc. really be so interested in anatomy? For medics, the reason for this interest is seemingly self evident--medical things happen to bodies and bits of the body. Surgical procedures are carried out on body parts; illnesses and injuries happen to the body and parts of the body. So, if we are to describe medicine, we need to start with anatomy. For molecular biologists, it is often not immediately obvious that biology and medicine join at the level of anatomy, especially in the study of disease processes and the treatment of disease, particularly through drug action.


Table of Contents

Part I Anatomical Ontologies for Model Organisms
Plant Structure Ontology (PSO)
Anatomy for Clinical Terminology
The Foundational Model of Anatomy Ontology
Towards a Disease Ontology
Part II Engineering and Linking of anatomy Ontologies
Ontology alignment and Merging
COBrA and COBrA-CT
Searching Biomedical Literature with Anatomy Ontologies
Part III Anatomy Ontologies and Spatio-Temporal Atlases
Anatomical Ontologies
Time in anatomy
The Edinburgh Mouse Atlas
The Smart Atlas
Part IV Anatomy Ontologies: Modelling Principles
Modeling Principles and Methodologies: Relations in anatomical Ontologies
Modelling Principles and Methodologies: Spatial Representation and Reasoning
CARO