Cover image for Cardiac regeneration using stem cells
Title:
Cardiac regeneration using stem cells
Publication Information:
Boca Raton : CRC Press, 2013
Physical Description:
viii, 366 pages : illustrations ; 24 cm.
ISBN:
9781466578395
Abstract:
"This book presents the current status and a future perspective of cardiac regeneration using pluripotent stem cells. To achieve cardiac regeneration using iPS cells, research workers have to understand many aspects of iPS cells, such as iPS cell generation methods, cardiomyocyte differentiation protocols, cardiomyocyte characterization methods, and tissue engineering and so on. This book is written by many top researchers with brand-new data in these fields and will certainly help readers to get a comprehensive picture of iPS cells in cardiac regeneration"--provided by publisher

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32050000000353 QP114.R45 C37 2013 Open Access Book Book
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30000010343136 QP114.R45 C37 2013 Open Access Book Book
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Summary

Summary

To achieve cardiac regeneration using pluripotent stem (iPS) cells, researchers must understand iPS cell generation methods, cardiomyocyte differentiation protocols, cardiomyocyte characterization methods, and tissue engineering. This book presents the current status and future possibilities in cardiac regeneration using iPS cells. Written by top researchers who present new data in these fields, this book reviews cardiac cell therapy for ischemic heart disease and explores in vitro generation of efficacious platelets from iPS cells. It also discusses modeling arrhythmogenic heart disease with patient-specific induced pluripotent stem cells.


Author Notes

Fukuda, Keiichi; Yuasa, Shinsuke


Table of Contents

Yoshinori Yoshida and Shinya YamanakaTomohisa Seki and Shinsuke YuasaHyun-Jai Cho and Yoo-Wook Kwon and Hyo-Soo KimHiroyuki YamagishiHideki Uosaki and Jun K. YamashitaAtsuhiko T. Naito and Seitaro Nomura and Ichiro Shiojima and Issei KomuroShinsuke YuasaFumiyuki HattoriTetsushi FurukawaMitsushige MurataYasuhiro Nakashima and Atsushi NakanoKatsuhisa Matsuura and Tatsuya ShimizuJong-Kook Lee and Akira Ito and Hiroyuki HondaHideaki Kanazawa and Konstantinos Malliaras and Michelle Kreke and Eduardo MarbánMasaki IedaDaniel Sinnecker and Alexander Goedel and Ralf J. Dirschinger and Alessandra Moretti and Karl-Ludwig LaugwitzNaoya Takayama and Koji EtoSatoshi Nori and Osahiko Tsuji and Kyoko Miura and Yoshiaki Toyama and Masaya Nakamura and Hideyuki Okano
Prefacep. v
1 Induced Pluripotent Stem Cellsp. 1
2 Human iPS Cell Generation Methods for Clinical Usagep. 20
3 Reprogramming and Regenerative Medicine: Unique Approach via Protein-derived iPSp. 35
4 Lessons from Heart Development to Regenerationp. 59
5 Directed and Systematic Differentiation of Cardiovascular Cells from Mouse and Human Pluripotent Stem Cellsp. 84
6 Wnt Signaling in Cardiogenesisp. 97
7 The Control of Proliferation of Pluripotent Stem Cell-derived Cardiomyocytesp. 118
8 How to Purify Cardiomyocytes for Research and Therapeutic Purposesp. 132
9 Ion Channel Expression and Function of iPSC-derived Cardiomyocytesp. 153
10 Pharmacology and Future Application of iPS Cell-derived Cardiomyocytesp. 173
11 Cardiac Regeneration Using Isl1-positive Cardiac Progenitor Cellsp. 185
12 Cell Sheet Engineering for Heart Tissue Repairp. 210
13 Construction of Functional Cardiovascular Tissues Using Magnetic Nanoparticlesp. 221
14 Cardiac Cell Therapy for Ischemic Heart Diseasep. 229
15 Induced Cardiomyocytes: Direct Reprogramming for Cardiac Regenerationp. 258
16 Modeling Arrhythmogenic Heart Disease with Patient-Specific Induced Pluripotent Stem Cellsp. 276
17 In vitro Generation of Efficacious Platelets from IPS Cellsp. 305
18 Neuron Regeneration Using iPS Cellsp. 315
Indexp. 333
Color Plate Sectionp. 335