Fereidoon Shahidi and Chi-Tang HoHong Lu and Xiaofeng Meng and Mao-Jung Lee and Chuan Li and Pius Maliakal and Chung S. YangS. P. J. Namal Senanayake and Fereidoon ShahidiJungil Hong and Chung S. YangZigang DongJen-Kun Lin and Min-Hsiung Pan and Chi-Tang Ho and Shoei-Yn Lin-ShiauMohamed M. RafiMarion Man-Ying Chan and Hsing-I Huang and John A. Mattiacci and Dunne FongMichihiro Mutoh and Hirofumi Matsui and Mami Takahashi and Takeji Takamura-Enya and Keiji WakabayashiSook J. Park and Cherl W. Park and Seck J. Kim and Jung K. Kim and Young R. Kim and Young S. Kim and Yeong L. HaItsuko Fukuda and Atsushi Kaneko and Yoshiyuki Yabushita and Iwao Sakane and Takami Kakuda and Kazuki Kanazawa and Gen-ichi Danno and Hitoshi AshidaTakashi Hashimoto and Wakana Ito and Takashi Furuyashiki and Takashi Sano and Ken-ichiro Minato and Masashi Mizuno and Kazuki Kanazawa and Gen-ichi Danno and Hitoshi AshidaBunsyo Shiotani and Hitoshi Ashida and Yuji Nonaka and Takashi Hashimoto and Kazuki Kanazawa and Gen-ichi DannoSachiko Kawakami and Ken-ichiro Minato and Toshikatsu Imamura and Yasuo Aizono and Masashi MizunoChunyuan Jin and Hongie Li and Masami Horikoshi and Kailai Sun and Kazunari K. YokoyamaChuan-Chuan Lin and Yao-Ping Lu and You-Rong Lou and Chi-Tang Ho and Harold H. Newmark and Christopher MacDonald and Keith W. Singletary and Mou-Tuan HuangMou-Tuan Huang and Yue Liu and Jian-Guo Xie and Harold H. Newmark and Chi-Tang HoYuji Naito and Shigenori Oka and Toshikazu YoshikawaWei Ding and Yue Liu and Robert T. Rosen and Geetha Ghai and Mou-Tuan HuangTakashi Furuyashiki and Sayaka Terashima and Hironobu Nagayasu and Atsushi Kaneko and Iwao Sakane and Takami Kakuda and Kazuki Kanazawa and Gen-ichi Danno and Hitoshi AshidaHitoshi Ashida and Takashi Hashimoto and Yuji Nonaka and Itsuko Fukuda and Kazuki Kanazawa and Gen-ichi Danno and Ken-ichiro Minato and Sachiko Kawakami and Masashi MizunoNagatoshi Ide and Makoto Ichikawa and Kenjiro Ryu and Jiro Yoshida and Takashi Sasaoka and Shin-ichiro Sumi and Hiromichi SumiyoshiKenjiro Ryu and Nagatoshi Ide and Makoto Ichikawa and Kozue Ogasawara and Robert T. RosenKazuo Miyashita and Eiichi Nara and Hiroaki Kubouchi and Tetsuya SuzukiAi Saiga and Toshihide NishimuraNicholi Vorsa and Amy B. Howell and L. Yeap Foo and Yinrong LuCatherine C. Neto and Xiaojun Yan and Brian T. Murphy and Kanayochukwu Azogu and Gerald B. HammondAkihiko Nagao and Eiichi Kotake-NaraP. G. Pietta and P. I. Mauri and M. Minoggio and C. Gardana and I. Iemoli and P. SimonettiYukihiro Kodera and Hiromichi Matsuura and Hiromichi Sumiyoshi and Shin-ichiro SumiYoshimasa NakamuraZhihua Liu and M. Mohamed Rafi and Nanqun Zhu and Kenjiro Ryu and Shengmin Sang and Chi-Tang Ho and Robert T. RosenYoshiyuki Nakamura and Mamoru Isemura and Sumio Hayakawa and Kouichi Saeki and Yu Koyama and Takashi Kimura and Masanori Kuroyanagi and Tadataka Noro and Kyoji Yoshino and Toshihiro TsuneyoshiLiangli YuShuichi Muranishi and Hideki Masuda and Susumu Kiyohara and Toshio Ueno and Chi-Tang HoZheng Wei and Toshihide NishimuraToshihide Nishimura

Preface	p. xiii
Overview and Perspectives
1. Food Factors in Health Promotion and Disease Prevention	p. 2
2. Bioavailability and Biological Activity of Tea Polyphenols	p. 9
3. Structured Lipids Enriched with Omega-3 and Omega-6 Highly Unsaturated Fatty Acids	p. 16
4. Effects of Tea Polyphenols on Arachidonic Acid Metabolism in Human Colon	p. 27
Signal Transduction and Gene Modulation
5. Prevention and Therapy of Cancer by Food Factors through p53-Dependent or -Independent Apoptosis	p. 40
6. Cancer Chemoprevention by Phytopolyphenols through Modulating Mitotic and Differentiating Signal Transduction Pathways	p. 50
7. Significance of Bcl-2 Protein Phosphorylation in Cancer Cells for Pharmaceutical and Nutraceutical Discovery	p. 72
8. Modulation of Cytokine Gene Expression by Curcumin	p. 86
9. Suppression of Transcriptional Activity of Gene Promoter for Cyclooxygenase-2 and Inducible Nitric Oxide Synthase in Colon Cancer Cells	p. 100
10. Divergent Cytotoxic Effects of Conjugated Linoleic Acid Isomers on NCI-N87 Cells	p. 113
11. Green Tea Extracts Prevent the Dioxin Toxicity through the Suppression of Transformation of the Aryl Hydrocarbon Receptor	p. 119
12. Preventive Effects of Food Components on Caspase-8-Mediated Apoptosis Induced by Dietary Carcinogen, Trp-P-1, in Rat Mononuclear Cells	p. 128
13. A Tryptophan Pyrolysis Product, 3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) but Not Its Metabolite Induces Apoptosis in Primary Cultured Rat Hepatocytes: Induction of CYP 1A Interfaces Trp-P-1-Induced Apoptosis	p. 141
14. Simulation of TNF-[alpha] and NO Production from Murine Macrophage by Water-Soluble Polysaccharides from Isaria japonica	p. 152
15. Role of Histone Acetyltransferase and Deacetylase in the Retinoic Acid-Induced Differentiation of F9 Cells	p. 163
Biomarker and Animal Models
16. In Vivo Inhibition of Mammary Carcinogenesis, Formation of DNA-Carcinogen Adducts, and Mammary Proliferation by Dietary Dibenzoylmethane	p. 178
17. Protective Effect of Dibenzoylmethane on Chemically- and UV Light-Induced Skin, Inflammation, Sunburn Lesions, and Skin Carcinogenesis in Mice	p. 196
18. Inflammatory Response in the Pathogenesis of Atherosclerosis and Its Prevention by Rosmarinic Acid, a Functional Ingredient of Rosemary	p. 208
19. Inhibitory Effects of Oral Administration of an Extract of Orange Peel in the Diet on Azoxymethane-Induced Formation of Aberrant Crypt Foci and Colon Tumor in CF-1 Mice	p. 213
20. Tea Extracts Modulate a Glucose Transport System in 3T3-L1 Adipocytes	p. 224
21. Suppression of Cytochrome P4501 a Subfamily in Mouse Liver by Oral Intake of Polysaccharides from Mushrooms, Lentinus edodes and Agaricus blazei	p. 235
Antioxidants
22. Antioxidants in Processed Garlic: Tetrahydro-[beta]-carboline Derivatives in Aged Garlic Extract	p. 250
23. Liquid Chromatography-Mass Spectrometry Method for Fructosylarginine, an Antioxidant in the Aged Garlic Extract	p. 264
24. Antioxidant Activity of Electrolized Sodium Chloride: Inhibitory Effect of Cathodic Solution Produced by the Electrolysis of a Dilute NaCl Solution on the Oxidation of Lipids and Lipid Related Compounds	p. 274
25. Antioxidative Peptides in Porcine Myofibrillar Protein Hydrolysates by Protease Treatment	p. 289
Fruits and Vegetables
26. Structure and Genetic Variation of Cranberry Proanthocyanidins That Inhibit Adherence of Uropathogenic P-Fimbriated E. coli	p. 298
27. Fractionation, Antioxidant Activity, and Cytotoxicity of Cranberry Fruit Extracts	p. 312
28. Conversion of Carotenoids to Retinoids and Other Oxidation Products	p. 322
29. Carotenoid and Polyphenol Content of Different Tomato Cultivars and Related Antioxidant Activity	p. 336
30. Garlic Chemistry: Chemical and Biological Properties of Sulfur-Containing Compounds Derived from Garlic	p. 346
31. Isothiocyanates as Inducers of Phase II Drug-Metabolizing Enzyme: Involvement of Cellular Redox Alteration	p. 358
32. Separation and Bioactivity of Diarylheptanoids from Lesser Galangal (Alpinia officinarum)	p. 369
33. Inhibition of Carcinogenesis by Tea Aqueous Non-Dialyzates Fractionated from Crude Tea Extracts	p. 381
Other Food Factors
34. Structural Modification to Improve Psyllium Functionality	p. 392
35. Effect of Antioxidants on Photosensitized Degradation of Methionine by Riboflavin	p. 400
36. Comparative Study of Glycans in Lactoferrin-a and Lactoferrin-b	p. 410
37. Influence of Endopeptidases and Aminopeptidases on the Production of Taste Peptides and Free Amino Acids in Muscle Foods	p. 419
Author Index	p. 431
Subject Index	p. 433