New cell adhesion research

Cell adhesion is the binding of a cell to another cell or to a surface or matrix. This book discusses the mitochondrial retrograde signalling, a recently discovered cellular signalling pathway, that may work in irradiated mammalian cells. The question whether radiation of visible and near IR radiation can activate this cellular signalling pathway is also reviewed. Novel experimental techniques that probe cellular forces exerted at the sites of adhesive contacts are examined, as well as how these forces can explain the roles of cell adhesion in orchestrating multi-cellular behaviour. Furthermore, the cell adhesion molecule trophinin is discussed, which is uniquely involved in the process of human embryo implantation. The roles of nano and microtopography in the substratum upon cell adhesion are addressed, as well as the effects of substratum and near-substratum mechanical properties on cell adhesion. CADM1, a new mast-cell adhesion molecule that mediates interaction with fibroblasts, nerves, and smooth muscles is discussed in this book, as well as carbon nanoparticles that are used as substrates for cell adhesion and growth. In addition, by reducing cell adhesion and inducing cell proliferation, diabetes increases the risk for oral carcinogenesis. The results of this animal model study are looked as well. Finally, the epithelial cell adhesion molecule, EpCAM, has been studied and subsequently discussed in this book.

Tiina I. KaruThuc-Nghi Nguyen and Soichiro YamadaMaryam Kabir-Salmani and Michiko N. FukudaEleri Lloyd Davies and Stephen HiscoxAdam CurtisAkihiko Ito and Man HagiyamaLucie Bacakova and Lubica Grausova and Marta Vandrovcova and Jiri Vacik and Aneta Frazcek and Stanislaw Blazewicz and Alexander Kromka and Bohuslav Rezek and Milan Vanecek and Milos Nesladek and Vaclav Svorcik and Vladimir Vorlicek and Milan KopecekChristos Yapijakis and Eleftherios VairaktarisKazuki Nakatani and Kazuo Ikeda and Yuji Nakajima and Shuichi SekiOlivier Gires and Dorothea Maetzel and Markus MunzTomas Sandberg and Anita Vitina

Preface	p. vii
Chapter I Attachment of Cells Is Regulated by Monochromatic Radiation in Red and Near Infrared Optical Region via a Novel Retrograde Mitochondrial Signaling Pathway	p. 1
Chapter II Forces at Adhesive Contacts	p. 39
Chapter III Cell Adhesion Molecules for Uterine Receptivity to Human Embryo Implantation	p. 53
Chapter IV Control of Cell-Cell Adhesion by Src Kinase: Implications for Cancer Progression	p. 69
Chapter V Novel Data on Cell Adhesion	p. 85
Chapter VI CADMI: A New Mast-Cell Adhesion Molecule That Mediates Interaction with Fibroblasts, Nerves and Smooth Muscles	p. 103
Chapter VII Carbon Nanoparticles as Substrates for Cell Adhesion and Growth	p. 119
Chapter VIII Diabetes Increases Risk for Oral Carcinogenesis by Induction of Cell Proliferation and Reduction of Cell Adhesion: An Animal Model Study	p. 185
Chapter IX Expression of Molecules with a Potential for Modulating Interaction with Extracellular Matrices on Hepatic Stellate Cells: Neural Cell Adhesion Molecules and Osteonectin	p. 205
Chapter X Epithelial Cell Adhesion Molecule EpCAM: Past, Present, and Future	p. 245
Short Communication	p. 257
Mucin Coatings for Controlled Cell-Material Interaction	p. 257
Index	p. 269

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