Title:
Principles of cellular engineering : understanding the biomolecular interface
Publication Information:
Burlington, MA : Elsevier Academic Press, 2006
ISBN:
9780123693921
Added Author:
Available:*
Library | Item Barcode | Call Number | Material Type | Item Category 1 | Status |
|---|---|---|---|---|---|
Searching... | 30000010107530 | QH604.2 P74 2006 | Open Access Book | Book | Searching... |
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Summary
Summary
This comprehensive work discusses novel biomolecular surfaces that have been engineered to either control or measure cell function at the atomic, molecular, and cellular levels. Each chapter presents real results, concepts, and expert perspectives of how cells interact with biomolecular surfaces, with particular emphasis on interactions within complex mechanical environments such as in the cardiovascular system. In addition, the book provides detailed coverage of inflammation and cellular immune response as a useful model for how engineering concepts and tools may be effectively applied to complex systems in biomedicine.
Table of Contents
| Part I Neutrophil Adhesion |
| Adhesion of flowing neutrophils to model vessel surfaces |
| Bond formation during cell compression |
| A flow chamber for capillary networks |
| Membrane dynamics during neutrophil recruitment |
| Hydrodynamic recruitment of cells to reactive surfaces |
| Part II Cell-Substrate Adhesion |
| Cell tensegrity models and cell-substrate interactions |
| Use of hydrodynamic shear stress to analyze cell adhesion |
| Traction forces exerted by endothelial cells |
| Control of endothelial cell adhesion by mechanotransmission |
| Part III Engineered Biomimetic Surfaces |
| Realistic atomistic modeling of protein adsorption to ceramic biomaterials |
| Cell responses to micro- and nano-topography |
