Title:
Hemodynamics and mechanobiology of endothelium
Personal Author:
Publication Information:
New Jersey : World Scientific, c2010
Physical Description:
viii, 370 p. : ill. ; 24 cm.
ISBN:
9789814280419
Available:*
Library | Item Barcode | Call Number | Material Type | Item Category 1 | Status |
---|---|---|---|---|---|
Searching... | 30000010294287 | QP105 H75 2010 | Open Access Book | Book | Searching... |
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Summary
Summary
The book represents a paradigm shift from the traditional static model of investigation of oxidative biology to the dynamic model of vascular oxidative stress. The investigation of vascular biology and cardiovascular medicine is made possible by the use of fluid dynamics, molecular signaling, genomic approach, tissue engineering, stem cell biology, and microfluidics. This is the first book to target a wide readership from academia to industry and government agencies in the field of cardiovascular diseases.
Table of Contents
Preface | p. v |
Chapter 1 Flow and Atherosclerosis | p. 1 |
Chapter 2 Shear Stress-Mediated Signal Transduction | p. 39 |
Chapter 3 Endothelial Glycocalyx Structure and Role in Mechanotransduction | p. 69 |
Chapter 4 Role of Krüppel-Like Factors in Shear Stress-mediated Vasoprotection | p. 97 |
Chapter 5 Rho Family Small GTPases in Shear Stress Signaling | p. 123 |
Chapter 6 Nitric Oxide and Endothelial Mitochondrial Function: Implications for Ischemia/Reperfusion | p. 153 |
Chapter 7 Genomic Approaches to Endothelial Cell Phenotyping | p. 179 |
Chapter 8 Endothelial Cell Proliferation and Differentiation in Response to Shear Stress | p. 213 |
Chapter 9 Vascular Differentiation of Stem Cells by Mechanical Forces | p. 247 |
Chapter 10 Tissue Engineered Blood Vessels: From the Bench to the Bedside and Back Again (Development of a Vascular Conduit for Use in Congenital Heart Surgery) | p. 271 |
Chapter 11 Design Implications for Endovascular Stents and the Endothelium | p. 291 |
Chapter 12 Vascular Mimetic Microfluidic Systems for the Study of Endothelial Activation and Leukocyte Recruitment in Models of Atherogenesis | p. 313 |
Chapter 13 Micro Shear Stress Sensors: From In Vitro to In Vivo Assessment of Inflammatory Responses | p. 331 |
Index | p. 361 |