Cover image for Pharmaceutical inhalation aerosol technology
Title:
Pharmaceutical inhalation aerosol technology
Series:
Drugs and pharmaceutical sciences ; 134
Edition:
2nd ed., rev. & expanded
Publication Information:
New York, NY : Marcel Dekker, 2004
ISBN:
9780824742539

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30000010077964 RS201.A42 P42 2004 Open Access Book Book
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Summary

Summary

This thoroughly revised and expanded reference provides authoritative discussions on the physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors, influencing the efficacy and utilization of pharmaceutical aerosol. It analyzes the latest science and developments in the generation, administration and characterization of these compounds, showcasing current clinical applications, the efficiency and limitations of major aerosol products and emerging aerosol therapies impacting the field.


Table of Contents

Factors governing aerosol deposition and targeting in the lung: physiology of the airwaysAnthony J. Hickey and David C. Thompson
pharmacology of therapeutic aerosolsDavid C. Thompson
targeting by depositionIgor Gonda
drug targeting to the lung - chemical and biochemical considerationsPeter A. Crooks
lung deposition simulationWarren Finlay
lung deposition imagingMyrna Dolovich
pharmacokinetics and pharmacodynamics of drugs delivered to the lungsG. Hochhaus
methods of generation, administration and characterization of aerosols - theoretical principles and devices used to generate aerosols for researchKeng H. Leong
The design and development of inhalation drug delivery systemsPaul J. Atkins and Nicholas P. Barker and Donald Mathisen
aerosol-filling equipment for the preparation of pressurized pack pharmaceutical formulationsChristophe Sirand and Jean-Pierre Varlet and Anthony J. Hickey
methods of aerosol particle size characterizationAnthony J. Hickey
summary of common approaches to pharmaceutical aerosol administrationAnthony J. Hickey
Clinical aspects of aerosol administration and future perspectives: therapeutic aerosols - an overview from a clinical perspectiveF. Charles Hiller
aerosolized pentamidine for treatment and prophylaxis of pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndromeBruce montgomery
The application of aerosolized antimicrobial therapies in lung infectionsDennis Williams
gene delivery to the lungJustin Hanesl
recent advances related to the systemic delivery of therapeutic molecules by inhalationDavid Edwards
modulated drug therapy with inhalation aerosols - revisitedRalph W. Niven
pulmonary delivery technology - advances of the last decade and potential for the new millenniumAndy Clark