Cover image for Drug interactions in infectious diseases
Title:
Drug interactions in infectious diseases
Series:
Infectious disease
Edition:
2nd ed.
Publication Information:
Totowa, NJ : Humana Press, 2005
ISBN:
9781588294555

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30000010102083 RM267 D78 2005 Open Access Book Book
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Summary

Summary

In this newly updated second edition, leading experts in antimicrobial pharmacology comprehensively review - and summarize for rapid access - important drug interactions that occur in the treatment of infectious, diseases. New to this book include a chapter outlining the regulatory perspective on interaction studies in drug development, as well as the design and analysis of studies utilizing CYP450 probes to characterize a drug's interaction potential. Comprehensive and highly practical, Drug Interactions in Infectious Disease, 2nd Ed., offers health care professionals treating infectious diseases in their daily practice a comprehensive source of quickly accessible information about drug interaction problems, their mechanisms of action, and the best strategies for their management in busy patient care.


Table of Contents

Keith Gallicano and George DrusanoAngela D. M. Kashuba and Joseph S. Bertino, Jr.Scott R. PenzakKellie Schoolar ReynoldsKimberly A. Struble and Stephen C. PiscitelliAlice TsengRocsanna Namdar and Steven C. Ebert and Charles A. PeloquinDavid R. P. GuayMelinda M. Neuhauser and Larry H. DanzigerPaul O. Gubbins and Scott A. McConnell and Jarrett R. AmsdenGregory M. SuslaKelly A. Harris and Kevin W. Garey and Keith A. RodvoldCurtis E. Haas and Jamie L. NelsenDouglas N. FishDavid E. Nix and Keith Gallicano
Forewordp. v
Prefacep. vii
Contributorsp. ix
1 Introduction to Drug Interactionsp. 1
2 Mechanisms of Drug Interactions I: Absorption, Metabolism, and Excretionp. 13
3 Mechanisms of Drug Interactions II: Transport Proteinsp. 41
4 Drug Interactions: Regulatory Perspectivep. 83
5 Drug Interactions With Antiretrovirals for HIV Infectionp. 101
6 Drugs for HIV-Related Opportunistic Infectionsp. 137
7 Drugs for Tuberculosisp. 191
8 Quinolonesp. 215
9 ß-Lactam Antibioticsp. 255
10 Antifungal Agentsp. 289
11 Miscellaneous Antibioticsp. 339
12 Drug-Food Interactionsp. 383
13 Drug-Cytokine Interactionsp. 431
14 Circumventing Drug Interactionsp. 463
15 Design and Data Analysis of Drug Interaction Studiesp. 483
Indexp. 507