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Summary
Summary
The Blood Group Antigen FactsBook -- winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine -- has been an essential resource in the hematology, transfusion and immunogenetics fields since its first publication in the late 1990s.The third edition of The Blood Group Antigen FactsBook has been completely revised, updated and expanded to cover all 33 blood group systems. It blends scientific background and clinical applications and provides busy researchers and clinicians with at-a-glance information on over 330 blood group antigens, including history and information on terminology, expression, chromosomal assignment, carrier molecular description, functions, molecular bases of antigens and phenotypes, effect of enzymes/chemicals, clinical significance, disease associations and key references.
Author Notes
Marion E. Reid, Ph.D., FIMBS, DSc (Hon.) is Head of the Laboratory of Immunochemistry and formerly the Director of the Laboratory of Immunohematology at New York Blood Center. Dr Retrained, as a medical technologist (Fellow Institute of the Institute of Biomedical Science in Hematology, Blood Transfusion, and Blood Group Serology) at the North East Metropolitan Blood Transfusion Service. Brentwood. She has a Master of Science decree in Clinical Science and a Ph.D. degree in Biochemistry.
Christine Lomas-Francis, MSc, FIBMS, is the Technical Director of the Laboratory of Immunohematology and Genomics at the New York Blood Center. Christine received her training at the Blood Group Unit of the Medical Research Council in London, England and originally relocated to the USA to join the Consultation and Education department at Gamma Biologicals, Inc.
Martin I. Olsson, M.D., Ph D., is a Professor in Transfusion Medicine at Lund University and the Medical Director of the Nordic Reference Laboratory for Genomic Blood Group Typing (Lund, Sweden). Dr. Olsson received his M.D. and Ph.D. at Lund University and has been a Visiting Scientist at the IBGRI in Bristol, U.K. in 1996 and a Visiting Associate Professor/Lecturer at Harvard Medical School, Boston, MA, USA from 2003 to 2008.
Table of Contents
Preface | p. ix |
Abbreviations | p. xi |
Section I The Introductory Chapters | |
1 Introduction | p. 3 |
Aims of this FactsBook | p. 3 |
Selection of entries | p. 3 |
Terminology | p. 6 |
References | p. 7 |
2 Organization of the data | p. 9 |
ISBT Blood Group Systems | p. 9 |
Number of Antigens | p. 9 |
Terminology | p. 9 |
Expression | p. 12 |
Gene | p. 12 |
Database accession numbers | p. 12 |
Molecular bases of antigens and phenotypes | p. 15 |
Amino acid sequence | p. 16 |
Carrier molecule | p. 17 |
Function | p. 18 |
Disease association | p. 18 |
Phenotypes | p. 18 |
Comments | p. 18 |
References | p. 18 |
ISBT Blood Group Antigens | p. 19 |
Terminology | p. 19 |
Occurrence | p. 19 |
Antithetical antigen | p. 19 |
Expression | p. 19 |
Molecular basis associated with antigen | p. 19 |
Effect of enzymes and chemicals on intact RBCs | p. 20 |
In vitro characteristics of alloantibody | p. 20 |
Clinical significance of alloantibody | p. 21 |
Autoantibody | p. 21 |
Comments | p. 22 |
References | p. 22 |
ISBT Blood Group Collections | p. 22 |
ISBT 700 Series of Low-Incidence Antigens | p. 22 |
ISBT 901 Series of High-Incidence Antigens | p. 22 |
References | p. 22 |
Section II The Blood Group Systems and Antigens | |
ABO Blood Group System | p. 27 |
MNS Blood Group System | p. 53 |
P1PK Blood Group System | p. 135 |
Rh Blood Group System | p. 147 |
Lutheran Blood Group System | p. 263 |
Kell Blood Group System | p. 297 |
Lewis Blood Group System | p. 347 |
Duffy Blood Group System | p. 361 |
Kidd Blood Group System | p. 373 |
Diego Blood Group System | p. 383 |
Yt Blood Group System | p. 415 |
Xg Blood Group System | p. 421 |
Scianna Blood Group System | p. 427 |
Dombrock Blood Group System | p. 439 |
Colton Blood Group System | p. 457 |
Landsteiner-Wiener Blood Group System | p. 467 |
Chido/Rodgers Blood Group System | p. 477 |
H Blood Group System | p. 489 |
Kx Blood Group System | p. 499 |
Gerbich Blood Group System | p. 505 |
Cromer Blood Group System | p. 525 |
Knops Blood Group System | p. 549 |
Indian Blood Group System | p. 567 |
Ok Blood Group System | p. 577 |
Raph Blood Group System | p. 585 |
John Milton Hagen Blood Group System | p. 591 |
I Blood Group System | p. 603 |
Globoside Blood Group System | p. 609 |
Gill Blood Group System | p. 615 |
Rh-Associated Glycoprotein Blood Group System | p. 619 |
FORS Blood Group System | p. 629 |
JR Blood Group System | p. 635 |
Lan Blood Group System | p. 641 |
Blood Group Collections | p. 647 |
Ii Blood Group Collection | p. 651 |
Er Blood Group Collection | p. 655 |
Globoside Blood Group Collection | p. 659 |
Unnamed Blood Group Collection | p. 665 |
Vel Blood Group Collection | p. 667 |
MN CHO Blood Group Collection | p. 671 |
The 700 Series of Low-Incidence Antigens | p. 677 |
The 901 Series of High-Incidence Antigens | p. 681 |
Section III Other Useful Facts | p. 691 |
Index | p. 731 |