Cover image for Modern biocatalysis : stereoselective and environmentally friendly reactions
Title:
Modern biocatalysis : stereoselective and environmentally friendly reactions
Publication Information:
New York : Wiley, 2009
Physical Description:
xxiii, 375 p. : ill. (some col.) ; 25 cm.
ISBN:
9783527320714

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30000010207399 TP248.65.E59 M62 2009 Open Access Book Book
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30000010293713 TP248.65.E59 M62 2009 Open Access Book Book
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Summary

Summary

This reference covers the wide and rapidly growing field of biocatalysis. It combines complementary expertise from such areas as microbiology, enzymology, molecular biology structural biology and organic chemistry, thus highlighting the interdisciplinary nature of the subject.
With its special focus on progress and new developments towards environmentally beneficial reactions with high levels of selectivity for the production of key compound classes, this book will enlighten both chemists and biologists as to the advances and opportunities existing in enzyme catalysis.


Author Notes

Wolf-Dieter Fessner obtained his PhD from the University of Freiburg, following which he carried out postdoctoral research at Harvard University with George Whitesides and at the University of Southern California with George Olah. Since 1998 he has been Full Professor of Organic Chemistry at the Technische Universität Darmstadt. His primary research interest is focused on the development of practical methods for enzymatic carbon-carbon bond formation and oligosaccharide synthesis, and on the interface between chemical and biological catalysis.

Thorleif Anthonsen is Professor of Organic Chemistry at The Norwegian University of Science and Technology, NTNU, in Trondheim. He has been a post doc/visiting scholar at Glasgow University, UK, at UCLA Los Angeles, with Donald Cram at MIT Cambridge, USA, with Alexander Klibanov and at Cytel Corporation, San Diego. He has led the biocatalysis group at NTNU whose research focused on synthesis of enantiopure compounds directed towards production of chiral drugs. In 2001 he initiated COST action D25, Applied Biocatalysis, which he also chaired from beginning to end. Professor Anthonsen's primary research interests are natural product chemistry and biocatalysis in organic chemistry.


Table of Contents

Fluorescence Assays for Biotransformations Immobilization as a Tool to Improve Enzymes Continuous-Flow
Microchannel Reactors with Surface-Immobilized Biocatalyst Activity and Stability of Proteases in Hydrophilic
Solvents Importance of Enzyme Formulation for the Activity and Enantioselectivity of Lipases in Organic Solvents
Direct Esterification with Dry Mycelium of Moulds: A (Stereo)selective, Mild and Efficient Method to Obtain
Structurally Diverse Esters Factors Affecting Enantioselectivity.
Allosteric Effects Kinetic Resolution of Sec-Alcohol in Non-Conventional Media Strategies for the Biocatalytic
Lipophilization of Phenolic Antioxidants Biocatalysis Applied to the Synthesis of Nucleoside Analogues Efficient
Fructooligosaccharide Synthesis with a Fructosyltransferase from Aspergillus Aculeatus Hydantoin Racemase:
The Key Enzyme for the Production of Optically Pure Alpha-Amino Acids Chemo-Enzymatic Deracemization
Methods Nitrilases from Filamentous Fungi Nitrilase and Nitrile Hydratase Catalyzed Enantioselective Synthesis of Nonproteinogenic
Amino Acids Nitrilases in the Enantioselective Synthesis of Alpha-Hydroxycarboxylic Acids UF-Membrane Bioreactors for Kinetics
Characterization of Nitrile Hydratase-Amidase Catalyzed Reactions: A Short Survey Enzymes Catalysing C-C Bond
Formation for the Synthesis of Monosaccharides Analogues Novel Strategies in Aldolase-Catalyzed Synthesis of Iminosugars Biocatalytic
Asymmetric Oxidations with Oxygen 2nd Generation Baeyer-Villiger Biocatalysts