Nanomedicine and cancer

The nanosciences are a rapidly expanding field of research with a wide applicability to all areas of health. They encompass a variety of technologies ranging from particles to networks and nanostructures. This book focuses on the application of nanomedicine and nanotechnology to cancer. It introduces nanocarriers, nanorods, nanoprobes nanoplatforms, nanorings, nanotubes nanowires, nano-sensor arrays and a variety of methodological techniques. This is done within the framework of numerous cancer types. Contributors are all leading experts and are carrying out groundbreaking work. The book is essential reading for oncologists, research scientists, doctors, health care professionals, pathologists, biologists, biochemists, chemists and physicists as well as those interested in disease and nanosciences or cancer in general.

Guillermo N. Armaiz-Pena and Bulent Ozpolat and Anil K. Sood and Gabriel Lopez-BeresteinConchita Tros de Ilarduya and Gloria Gonzalez-AseguinolazaCheng-Lung Chen and Yang-Yuan ChenSami Nazzal and Paul W. SylvesterDenyl L. Troyer and Stefan H. BossmannDongfang Liu and Ning GuJosé L. Arias and Margarita López-Viota and M^a Adolfina RuizHsin-ya Chien and Sandra Fok and Vanisri Raviraj and Jiwon Lee and Louise Cole and J. Guy Lyons and Lilian SoonLu Wang and Cong LiHai Ming Fan and Malini OlivoMurugan Veerapandian and Min-Ho LeeP.V. Asharani and Luxmi Fatimathas and Hui Kheng Lim and Suresh Valiyaveettil and M. Prakash HandeTianyi M. Krupka and Agata A. ExnerJosé L. AriasMansoor M. Amiji and Francis Hornicek and Zhenfeng DuanS. Hunter Walker and David C. MuddimanSilvano Dragonieri and Giorgio Pennazza and Marco SantonicoZiyu Wang and Dongsheng ZhangLicheng Dai and Xing Yao and Jing ZhongErik C. Dreaden and Mostafa A. El-Sayed and Ivan H. El-Sayed

Preface	p. v
Section 1 General Aspects, Methods and Techniques
1 Nanomedicine-based use of siRNA in Cancer	p. 3
2 Nanocarriers for Gene Delivery	p. 26
3 Cancer Cell Photothermolysis and Gold Nanorod Surface Plasmons	p. 46
4 Tocotrienol Loaded Lipid Nanoparticles in Cancer	p. 63
5 Utilization of Magnetic Nanoparticles for Cancer Therapy	p. 84
6 Nanoparticle Probes and Molecular Imaging in Cancer	p. 105
7 Iron and Ethylcellulose Nanoplatforms for Cancer Targeting	p. 123
8 Matrix Scaffolds in Cancer Cell Biology; Physiological Representation and Nanoscale Characterisation	p. 142
9 Fluorescence Nanoprobe Imaging Tumor by Sensing the Acidic Microenvironment	p. 160
10 Magnetic Nanorings and Nanotubes for Cancer Detection and Therapy	p. 183
11 Silicon Nanowire Arrays and other Silicon Nanostructures and Their Clinical Applications to Cancer	p. 204
12 Silver Nanomedicine and Cancer	p. 224
13 Nanobubbles and Their Putative Application to Cancer Medicine	p. 246
14 Nano-Strategies in the Delivery of Antitumor Drugs to Cancer	p. 268
15 Gene Silencing with siRNA Encapsulated Nanoparticles to Overcome Tumor Multidrug Resistance	p. 290
16 Nano-flow Liquid Chromatography Mass Spectrometric Analysis of Glycans in Cancer	p. 307
Section 2 Specific Cancers and Areas of Focus
17 Composite Nano-Sensor Arrays Technology in Lung Cancer	p. 331
18 Nano Arsenic Oxide (As 2 O 3 )/(Fe 2 O 3 ) Iron Oxide Complexes for Liver Cancer	p. 344
19 Hepatocellular Carcinoma and Midkine-antisense Oligonucleotide-loaded Nanoparticles	p. 360
20 Nanotechnology and Nanostructures Applied to Head and Neck Cancer	p. 373
Index	p. 397
About the Editors	p. 403
Color Plate Section	p. 405

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