Available:*
Library | Item Barcode | Call Number | Material Type | Item Category 1 | Status |
|---|---|---|---|---|---|
Searching... | 30000004300277 | TP248.65.P76 I52 2005 | Open Access Book | Book | Searching... |
On Order
Summary
Summary
This book covers both basic elements and the state-of-the-art in applications of proteomics. The first section gives an introduction to the field, from differential approaches to functional proteomics, including yeast two-hybrid, mass spectrometry, mapping of post-translational modifications, and NMR spectroscopy. The second section offers a complete picture of industry studies in proteomics for human health and biotechnology applications. The final section addresses the future, looking at the most promising areas such as protein arrays and the integration of genomic and proteomic tools.
Author Notes
DANIEL FIGEYS, Ph.D., is the Director of the Ottowa Institute of Systems Biology. Prior to joining the institute, Dr. Figeys was senior vice president, systems biology at MDS Proteomics and a research officer at the NRC-Canada. He did his postdoc at the Department of Molecular Biotechnology in Seattle with Dr. R. Aebersold.
Table of Contents
| Preface |
| Contributors |
| 1 Proteomics: The Basic OverviewDaniel Figeys |
| 2 Mapping Protein-Protein InteractionsDaniel Figeys |
| 3 Protein Post-Translational Modifications: Phosphorylation Site Analysis Using Mass SpectrometryRoland S. Annan and Francesca Zappacosta |
| 4 The Use of High Throughput Crystallography and In Silico Methods for Structure Based Drug DesignLeslie W. Tarr and Andy J. Jennings and Duncan E. McRee |
| 5 High Throughput Analysis of Protein Structure by H/D Exchange (H/D-Ex) Mass SpectrometryYoshitomo Hamuro and Patricia C. Weber and Patrick R. Griffin |
| 6 Proteomics Technologies for Identification and Validation of Protein TargetsJohn E. Hale and Weija Ou and Pavel Shiyanov and Michael D. Knierman and James R. Ludwig |
| 7 Proteomics Discovery of BiomarkersRobert Mass?? and Bernard F. Gibbs |
| 8 Industrial-Scale Proteomics Analysis of Human PlasmaKeith Rose |
| 9 Chemical Genomics: Targets on DisplaySteve Doberstein and Philip W. Hammond and Ren?? S. Hubert |
| 10 Bioinformatics for ProteomicsChristian Ahrens and Hans Jespersen and Soeren Schandorff |
| 11 Protein ArraysDavid S. Wilson and Steffen Nock |
| Index |
