Proteases in the brain

Title:

Series:

Proteases in biology and disease

Publication Information:

New York : Springer, 2005

ISBN:

9780387231006

Subject Term:

Brain -- Pathophysiology

Added Author:

Available:*

Library	Item Barcode	Call Number	Material Type	Item Category 1	Status
Searching... PSZ JB	30000010082047	RC347 P76 2005	Open Access Book	Book	Searching... Unknown

In all organs of the body, proteases have critical roles to play both in normal development and functioning and in disease states. The brain is no exception to this, with proteases having emerging roles in synaptic plasticity, memory, neurodegenerative disorders such as Alzheimer's, Parkinson's and prion diseases, ischemia and traumatic brain injury, inflammatory and infectious diseases, and tumor progression. Proteases in the Brain brings together a wide range of topics under this central theme and highlights the large number of proteases involved in these normal and disease processes.

Proteases in the Brain reviews the role and regulation of proteases in, Alzheimer's disease, brain ischemia and traumatic brain injury, human glioma, inflammatory and infectious diseases of the central nervous system, metabolism of the prion protein, modulating synaptic activity, multiple sclerosis, neuronal plasticity and memory consolidation, Parkinson's disease, processing, conversion and inactivation of neuropeptides.

Proteases in the Brain is a timely and useful source of information both for those well-versed in the role of proteases in the brain, and for those who are beginning to realize the important role of this family of enzymes in brain function and dysfunction.

Hans-Gert BernsteinStephen J. Crocker and Patrice D. Smith and David S. ParkSwapan K. RaySusan M. Knoblach and Alan I. FadenBernd C. Kieseier and Fabian BernalStefan Brocke and Andreas Steinbrecher and Aliza Biton and Maya Ratner and Vera Preller and Bettina Rotthauwe and Sabine Wrenger and Dirk ReinholdSajani S. Lakka and Jasti S. RaoM. Antonieta Valenzuela and Luis Cartier and Aron D. Mosnaim and Marion E. Wolf and Ana Maria Kettlun and Lucia Collados and Lorena GarciaMathias Hallberg and Pierre Le Greves and Fred NybergJohn W. Wright and Joseph W. HardingNobuko Mataga and Takao K. HenschHiroshi NakanishiBarry W. FestoffCorey C. Ford and Gary W. Rosenberg

Chapter 1 Proteases and Alzheimer Disease: Present Knowledge and Emerging Concepts of Therapy	p. 1
Chapter 2 Calpain Proteolysis and the Etiology of Parkinson's Disease: An Emerging Hypothesis	p. 25
Chapter 3 Cysteine Proteases in Neuronal Death in Brain Ischemia	p. 63
Chapter 4 Proteases in Traumatic Brain Injury	p. 79
Chapter 5 Proteases in CNS Infection and Inflammation	p. 109
Chapter 6 Dipeptidyl Peptidase IV Regulates T Cell Function in CNS Inflammation	p. 139
Chapter 7 Role and Regulation of Proteases in Human Glioma	p. 151
Chapter 8 Proteases and Prion Diseases	p. 179
Chapter 9 Neuropeptide Processing	p. 203
Chapter 10 Proteases and Neuronal Plasticity	p. 235
Chapter 11 Serine Proteases and Neuronal Plasticity in vivo	p. 271
Chapter 12 Proteases and Synaptic Activity	p. 303
Chapter 13 Role of Proteinase-Activated Receptors in Brain Function	p. 323
Chapter 14 Matrixmetalloproteinases and Neuroinflammation in Multiple Sclerosis	p. 351
Index	p. 373

Available:*

On Order

Summary

Summary

Table of Contents