Title:
Ocular angiogenesis : diseases, mechanisms, and therapeutics
Personal Author:
Series:
Opthalmology research
Publication Information:
Totowa, NJ : Humana Press Inc., 2006
ISBN:
9781597450478
Subject Term:
Added Author:
Added Corporate Author:
Electronic Access:
Full Text
Genre:
DSP_RESTRICTION_NOTE:
Accessible within UTM campus
Available:*
Library | Item Barcode | Call Number | Material Type | Item Category 1 | Status |
---|---|---|---|---|---|
Searching... | EB000323 | EB 000323 | Electronic Book | 1:EBOOK | Searching... |
On Order
Summary
Summary
Leading academic and pharmaceutical researchers and clinicians from many disciplines synthesize and summarize current clinical and basic knowledge concerning abnormal growth of blood vessels in the eye, the cause of major neovascular eye diseases. The authors also identify and assess the most promising approaches with potential for commercial exploitation and discuss the challenges encountered in developing therapeutics for ocular neovascular diseases. Highlights include illuminating chapters on gene therapy and novel drug delivery systems and excellent summaries of the newest therapeutic approaches.
Table of Contents
Preface | p. v |
Contributors | p. xi |
Companion CD | p. xv |
I Angiogenic Diseases | |
1 Age-Related Macular Degeneration | p. 3 |
2 Endogenous Angiogenic Inhibitors in Diabetic Retinopathy | p. 23 |
3 Corneal Angiogenesis | p. 45 |
4 Polypoidal Choroidal Vasculopathy | p. 73 |
5 Myopic Choroidal Neovascularization | p. 85 |
6 Mechanisms of the Formation and Stability of Retinal Blood Vessels | p. 101 |
7 Neovascular Glaucoma | p. 127 |
8 Eales' Disease | p. 149 |
9 Angiogenesis and Ocular Tumorigenesis | p. 161 |
10 Genetics of Ocular Vascular Disease | p. 173 |
II Endogenous Promoters And Inhibitors Of Angiogenesis | |
11 Vascular Endothelial Growth Factor and Retinal Diseases | p. 191 |
12 The Role of Fibroblast Growth Factors in Ocular Angiogenesis | p. 205 |
13 Control of Neovascularization and Cell Survival in the Eye by PEDFJoyce Tombran-Tink and Colin J. Barnstable | |
14 Thrombospondin: Guarding the Clear View | p. 233Arin Auro |
15 Regulation of Ocular Angiogenesis by Matrix Proteases and Tissue Inhibitors of Metalloproteinases | p. 257 |
16 Integrins in Ocular Angiogenesis | p. 279 |
17 Ocular Inflammation and Neovascularization | p. 291 |
III Therapeutics And Delivery For Angiogenic Eye Diseases | |
18 Anti-VEGF Therapies for Diseases of the Retina and Choroid | p. 309 |
19 Anecortave Acetate: A Novel Ocular Angiostatic Agent | p. 341 |
20 Gene Therapy for Neovascular Retinopathies | p. 355 |
21 Noninvasive Delivery of DNA Into the Eye | p. 373 |
22 Novel Drug Delivery Systems for Posterior Segment Ocular Disease | p. 393 |
Index | p. 409 |