Cover image for Supercritical fluid technology for drug product development
Title:
Supercritical fluid technology for drug product development
Series:
Drugs and pharmaceutical sciences ; 138
Publication Information:
New York, NY : Marcel Dekker, 2004
ISBN:
9780824748050

Available:*

Library
Item Barcode
Call Number
Material Type
Item Category 1
Status
Searching...
30000010077951 RS192 S96 2004 Open Access Book Book
Searching...

On Order

Summary

Summary

Interconnecting the fundamentals of supercritical fluid (SCF) technologies, their current and anticipated utility in drug delivery, and process engineering advances from related methodological domains and pharmaceutical applications, this volume unlocks the potential of supercritical fluids to further the development of improved pharmaceutical products-from drug powders for respiratory delivery to drug delivery systems for controlled release.


Table of Contents

Janice L. Panza and Eric J. BeckmanMamata MukhopadhyayJerzy Baldyga and Marek Henczka and Boris Y. ShekunovGerard Charbit and Elisabeth Badens and Olivier BoutinKeith P. Johnston and Sandro R. P. DaRocha and C. Ted Lee and Ge Li and Matthew Z. YatesBoris Y. ShekunovAlbert H. L. Chow and Henry H. Y. Tong and Boris Y. ShekunovSergei G. KazarianNagesh Bandi and Christopher B. Roberts and Ram B. Gupta and Uday B. KompellaB. L. Knutson and Marazban SarkariPhilip G. JessopTerry A. BergerM. D. Luque de Castro and A. Jurado-Lopez and J. L. Luque-GarciaJerry W. KingJean-Yves Clavier and Michel Perrut
Prefacep. iii
Contributorsp. xi
Part I. Fundamentals
1. Chemistry and Materials Design for CO[subscript 2] Processingp. 1
2. Phase Equilibrium in Solid-Liquid-Supercritical Fluid Systemsp. 27
3. Fluid Dynamics, Mass Transfer, and Particle Formation in Supercritical Fluidsp. 91
4. Methods of Particle Productionp. 159
Part II. Drug Delivery Applications
5. Colloid and Interface Science for CO[subscript 2]-Based Pharmaceutical Processesp. 213
6. Production of Powders for Respiratory Drug Deliveryp. 247
7. Control of Physical Forms of Pharmaceutical Substancesp. 283
8. Supercritical Fluid Impregnation of Polymers for Drug Deliveryp. 343
9. Formulation of Controlled-Release Drug Delivery Systemsp. 367
10. Processing of Biological Materialsp. 411
Part III. Other Applications and Scale-Up Issues
11. Asymmetric Catalysis in Supercritical Fluidsp. 461
12. Analytical and Semipreparative Supercritical Fluid Chromatography in Drug Discoveryp. 497
13. Drug Extractionp. 539
14. Development and Potential of Critical Fluid Technology in the Nutraceutical Industryp. 579
15. Scale-Up Issues for Supercritical Fluid Processing in Compliance with GMPp. 615
Indexp. 653