Title:
Supercritical fluid technology for drug product development
Series:
Drugs and pharmaceutical sciences ; 138
Publication Information:
New York, NY : Marcel Dekker, 2004
ISBN:
9780824748050
Available:*
Library | Item Barcode | Call Number | Material Type | Item Category 1 | Status |
---|---|---|---|---|---|
Searching... | 30000010077951 | RS192 S96 2004 | Open Access Book | Book | Searching... |
On Order
Summary
Summary
Interconnecting the fundamentals of supercritical fluid (SCF) technologies, their current and anticipated utility in drug delivery, and process engineering advances from related methodological domains and pharmaceutical applications, this volume unlocks the potential of supercritical fluids to further the development of improved pharmaceutical products-from drug powders for respiratory delivery to drug delivery systems for controlled release.
Table of Contents
Preface | p. iii |
Contributors | p. xi |
Part I. Fundamentals | |
1. Chemistry and Materials Design for CO[subscript 2] Processing | p. 1 |
2. Phase Equilibrium in Solid-Liquid-Supercritical Fluid Systems | p. 27 |
3. Fluid Dynamics, Mass Transfer, and Particle Formation in Supercritical Fluids | p. 91 |
4. Methods of Particle Production | p. 159 |
Part II. Drug Delivery Applications | |
5. Colloid and Interface Science for CO[subscript 2]-Based Pharmaceutical Processes | p. 213 |
6. Production of Powders for Respiratory Drug Delivery | p. 247 |
7. Control of Physical Forms of Pharmaceutical Substances | p. 283 |
8. Supercritical Fluid Impregnation of Polymers for Drug Delivery | p. 343 |
9. Formulation of Controlled-Release Drug Delivery Systems | p. 367 |
10. Processing of Biological Materials | p. 411 |
Part III. Other Applications and Scale-Up Issues | |
11. Asymmetric Catalysis in Supercritical Fluids | p. 461 |
12. Analytical and Semipreparative Supercritical Fluid Chromatography in Drug Discovery | p. 497 |
13. Drug Extraction | p. 539 |
14. Development and Potential of Critical Fluid Technology in the Nutraceutical Industry | p. 579 |
15. Scale-Up Issues for Supercritical Fluid Processing in Compliance with GMP | p. 615 |
Index | p. 653 |