Cover image for Biomimetic materials and design : biointerfacial startegies, tissue engineering, and targeted drug delivery
Title:
Biomimetic materials and design : biointerfacial startegies, tissue engineering, and targeted drug delivery
Publication Information:
New York : Marcel Dekker, 2002
ISBN:
9780824707910
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Item Category 1
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30000010128038 QP517.B56 B54 2002 Open Access Book Book
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Summary

Summary

Detailing techniques in wound healing and reconstruction, this reference describes the mechanisms and architecture of biological systems to formulate and design natural and synthetic compounds, degradable and non-degradable scaffolds, and targeted drug delivery devices. It offers strategies to control adhesive interactions, elicit specific cellular responses, and improve the biocompatibility, performance, and durability of prosthetic materials. Covering advances in the field, the book discusses the effect of topographical features on cell behaviors such as orientation, adhesion, migration, proliferation, and differentation.


Table of Contents

Sarah E. Ochsenhirt and Matthew Tirrell and Gregg B. Fields and Angela K. DillowAndres J. Garcia and David M. Collard and Benjamin G. Keselowsky and Sarah M. Cutler and Nathan D. Gallant and Benjamin A. Byers and Sean N. StephanssonGregory M. Harbers and Thomas A. Barber and Ranee A. Stile and Dale R. Sumner and Kevin E. HealyGeorge A. Abrams and Ana I. Teixeira and Paul F. Nealey and Christopher J. MurphyXue-Long Sun and Keith M. Faucher and Elliot L. ChaikofJeffrey D. Carbeck and Jean E. SchwarzbauerAndrea L. Koenig and David W. GraingerScott M. Cannizzaro and Robert LangerPamela K. Kreeger and Lonnie D. SheaHoward W. T. MatthewJane S. Tjia and Prabhas V. MogheJessica O. Winter and Christine E. SchmidtXudong Cao and Molly S. ShoichetMark E. Byrne and David B. Henthorn and Yanbin Huang and Nicholas A. PeppasPatrick S. Stayton and Allan S. Hoffman and Oliver W. Press and Niren Murthy and Chantal Lackey and Charles Cheung and Tsuyoshi Shimoboji and Zhongli Ding and Fiona Black and Jean S. Campbell and Nelson Fausto and Themis R. Kyriakides and Paul BornsteinThomas D. Dziubla and Marc C. Torjman and Jeffrey I. Joseph and Anthony M. LowmanKristyn S. Masters and Jennifer L. WestCindy W. Wu and Annelise E. BarronJames W. Schneider
Prefacep. iii
Contributorsp. xi
I. Biointerfacial Strategies
1. Use of Supported Thin Films of Peptide Amphiphiles as Model Systems of the Extracellular Matrix to Study the Effects of Structure-Function Phenomena on Cell Adhesionp. 1
2. Engineering of Integrin-Specific Biomimetic Surfaces to Control Cell Adhesion and Functionp. 29
3. Mimetic Peptide-Modified Materials for Control of Cell Differentiationp. 55
4. Effects of Substratum Topography on Cell Behaviorp. 91
5. Cytomimetic Biomaterials: Fabrication, Characterization, and Applicationsp. 139
6. Micro- and Nanoscale Organizations of Proteins Modulate Cell-Extracellular Matrix Interactions: Lessons for the Design of Biomaterialsp. 159
7. Cell Adhesion-Dependent Signaling Pathways on Biomaterials Surfacesp. 187
II. Tissue Engineering
8. Biomaterials: Synthetic and Engineering Strategiesp. 251
9. Scaffolds for Directing Cellular Responses and Tissue Formationp. 283
10. Chitosan as a Molecular Scaffold for Biomimetic Design of Glycopolymer Biomaterialsp. 311
11. "Cell-Internalizable" Ligand Microinterfaces on Biomaterials: Design of Regulatory Determinants of Cell Migrationp. 335
12. Biomimetic Strategies and Applications in the Nervous Systemp. 375
13. Tissue Engineering Strategies for Axonal Regeneration Following Spinal Cord Injuryp. 417
III. Targeted Drug Delivery
14. Micropatterning Biomimetic Materials for Bioadhesion and Drug Deliveryp. 443
15. Bioinspired Engineering of Intelligent Drug Delivery Systems and Protein-Polymer Conjugatesp. 471
16. Implantable Drug Delivery Devices: Design of a Biomimetic Interfacial Drug Delivery Systemp. 507
17. Pharmacologically Active Biomaterialsp. 533
18. Biomimetic Lung Surfactant Replacementsp. 565
19. Peptide Nucleic Acid (PNA) Conjugates in Biotechnologyp. 635
Indexp. 669