Title:
Biomimetic materials and design : biointerfacial startegies, tissue engineering, and targeted drug delivery
Publication Information:
New York : Marcel Dekker, 2002
ISBN:
9780824707910
Subject Term:
Available:*
Library | Item Barcode | Call Number | Material Type | Item Category 1 | Status |
---|---|---|---|---|---|
Searching... | 30000010128038 | QP517.B56 B54 2002 | Open Access Book | Book | Searching... |
On Order
Summary
Summary
Detailing techniques in wound healing and reconstruction, this reference describes the mechanisms and architecture of biological systems to formulate and design natural and synthetic compounds, degradable and non-degradable scaffolds, and targeted drug delivery devices. It offers strategies to control adhesive interactions, elicit specific cellular responses, and improve the biocompatibility, performance, and durability of prosthetic materials. Covering advances in the field, the book discusses the effect of topographical features on cell behaviors such as orientation, adhesion, migration, proliferation, and differentation.
Table of Contents
Preface | p. iii |
Contributors | p. xi |
I. Biointerfacial Strategies | |
1. Use of Supported Thin Films of Peptide Amphiphiles as Model Systems of the Extracellular Matrix to Study the Effects of Structure-Function Phenomena on Cell Adhesion | p. 1 |
2. Engineering of Integrin-Specific Biomimetic Surfaces to Control Cell Adhesion and Function | p. 29 |
3. Mimetic Peptide-Modified Materials for Control of Cell Differentiation | p. 55 |
4. Effects of Substratum Topography on Cell Behavior | p. 91 |
5. Cytomimetic Biomaterials: Fabrication, Characterization, and Applications | p. 139 |
6. Micro- and Nanoscale Organizations of Proteins Modulate Cell-Extracellular Matrix Interactions: Lessons for the Design of Biomaterials | p. 159 |
7. Cell Adhesion-Dependent Signaling Pathways on Biomaterials Surfaces | p. 187 |
II. Tissue Engineering | |
8. Biomaterials: Synthetic and Engineering Strategies | p. 251 |
9. Scaffolds for Directing Cellular Responses and Tissue Formation | p. 283 |
10. Chitosan as a Molecular Scaffold for Biomimetic Design of Glycopolymer Biomaterials | p. 311 |
11. "Cell-Internalizable" Ligand Microinterfaces on Biomaterials: Design of Regulatory Determinants of Cell Migration | p. 335 |
12. Biomimetic Strategies and Applications in the Nervous System | p. 375 |
13. Tissue Engineering Strategies for Axonal Regeneration Following Spinal Cord Injury | p. 417 |
III. Targeted Drug Delivery | |
14. Micropatterning Biomimetic Materials for Bioadhesion and Drug Delivery | p. 443 |
15. Bioinspired Engineering of Intelligent Drug Delivery Systems and Protein-Polymer Conjugates | p. 471 |
16. Implantable Drug Delivery Devices: Design of a Biomimetic Interfacial Drug Delivery System | p. 507 |
17. Pharmacologically Active Biomaterials | p. 533 |
18. Biomimetic Lung Surfactant Replacements | p. 565 |
19. Peptide Nucleic Acid (PNA) Conjugates in Biotechnology | p. 635 |
Index | p. 669 |